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IL-10R beta/IL-10RB Protein, Human, Recombinant (hFc)

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货号 TMPJ-00213

别名 Interleukin-10 receptor subunit β(IL10RB), Interleukin-10 receptor subunit beta(IL10RB), Interleukin-10 receptor subunit 2, Cytokine receptor family 2 member 4, Cytokine receptor class-II member 4

Interleukin-10 receptor subunit beta(IL10RB), also known as Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,Interleukin-10 receptor subunit 2, belongs to the type II cytokine receptor family. IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.

IL-10R beta/IL-10RB Protein, Human, Recombinant (hFc)
其他形式的 “IL-10R beta/IL-10RB Protein, Human, Recombinant (hFc)”:
IL-10R beta/IL-10RB Protein, Human, Recombinant (His & hFc)
IL-10R beta/IL-10RB Protein, Human, Recombinant (His)
IL-10R beta/IL-10RB Protein, Mouse, Recombinant (hFc)
IL-10R beta/IL-10RB Protein, Mouse, Recombinant (His)
IL-10R beta/IL-10RB Protein, Rat, Recombinant (hFc)

IL-10R beta/IL-10RB Protein, Human, Recombinant (hFc)

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货号 TMPJ-00213 别名 Interleukin-10 receptor subunit β(IL10RB), Interleukin-10 receptor subunit beta(IL10RB), Interleukin-10 receptor subunit 2, Cytokine receptor family 2 member 4, Cytokine receptor class-II member 4

Interleukin-10 receptor subunit beta(IL10RB), also known as Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,Interleukin-10 receptor subunit 2, belongs to the type II cytokine receptor family. IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.

规格价格库存数量
5 μg
¥ 243
6-8日内发货
10 μg
¥ 380
6-8日内发货
20 μg
¥ 596
5日内发货
50 μg
¥ 1,170
5日内发货
100 μg
¥ 1,790
5日内发货
200 μg
¥ 2,830
5日内发货
500 μg
¥ 5,130
5日内发货
1 mg
¥ 6,720
5日内发货
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产品介绍

生物活性
产品描述
Interleukin-10 receptor subunit beta(IL10RB), also known as Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,Interleukin-10 receptor subunit 2, belongs to the type II cytokine receptor family. IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Interleukin-10 receptor subunit beta(IL10RB), also known as Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,Interleukin-10 receptor subunit 2, belongs to the type II cytokine receptor family. IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.
种属
Human
表达系统
HEK293 Cells
标签C-hFc
蛋白编号Q08334
氨基酸序列Met20-Ser220
蛋白构建Met20-Ser220
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名Interleukin-10 receptor subunit β(IL10RB), Interleukin-10 receptor subunit beta(IL10RB), Interleukin-10 receptor subunit 2, Cytokine receptor family 2 member 4, Cytokine receptor class-II member 4
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量75-95 KDa (reducing condition)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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剂量转换

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技术支持

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