- 全部删除
- 您的购物车当前为空
Anti-SSTR2 Antibody (1Z419) 是一种抗体,靶向 SSTR2。Anti-SSTR2 Antibody (1Z419) 可用于 ELISA, IHC。
Anti-SSTR2 Antibody (1Z419) 是一种抗体,靶向 SSTR2。Anti-SSTR2 Antibody (1Z419) 可用于 ELISA, IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,315 | 5日内发货 | |
100 μL | ¥ 2,180 | 5日内发货 |
产品描述 | Anti-SSTR2 Antibody (1Z419) is an antibody targeting SSTR2. Anti-SSTR2 Antibody (1Z419) can be used in ELISA, IHC. |
别名 | somatostatin receptor 2 |
Ig Type | Rabbit IgG |
克隆号 | 1Z419 |
交叉反应 | Human |
验证活性 | IHC image of TMAH-01133 diluted at 1:100 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
应用 | |
推荐剂量 | IHC:1:50-1:200. |
抗体种类 | Monoclonal |
亚细胞定位 | Cell membrane; Multi-pass membrane protein. Cytoplasm. Note=Located mainly at the cell surface under basal conditions. Agonist stimulation results in internalization to the cytoplasm. |
构建方式 | Recombinant Antibody |
纯化方式 | Affinity-chromatography |
性状 | Liquid |
缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization. |
偶联 | Unconjugated |
免疫原 | A synthetic peptide: Human Somatostatin Receptor 2 |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | Neuroscience, Cancer, Metabolism |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
评论内容