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Ponsegromab

Name: Ponsegromab
Brand: TargetMol
SKU: T76774
Price: 2320 CNY
Availability: InStock
Rating: 5 (10 reviews)

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产品编号 T76774Cas号 2368950-15-4

别名 PF 06946860

Ponsegromab (PF 06946860) 是一种具有选择性和有效性的人源化抗 GDF15 抗体抑制剂。 Ponsegromab 具有抗恶病质活性，通过与 GDF15 结合来阻止其与 GFRAL 结合，从而中断 GDF15/GFRAL 介导的信号传导。 Ponsegromab 具有潜在的抗癌活性，可用于治疗患有癌症厌食-恶病质综合征的癌症患者。

Ponsegromab

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Ponsegromab

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产品编号 T76774 别名 PF 06946860Cas号 2368950-15-4

规格	价格	库存
1 mg	¥ 2,320	In stock
5 mg	¥ 6,220	In stock
10 mg	¥ 8,390	In stock
25 mg	¥ 12,300	In stock
50 mg	¥ 16,800	In stock

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TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

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选择批次:

浓度:6.36 mg/mL

纯度:> 95%

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资源下载

COA SDS-PAGE SEC-HPLC 产品操作手册

产品介绍

生物活性

产品描述	Ponsegromab (PF 06946860) is a selective and effective humanized anti-GDF15 antibody inhibitor. Ponsegromab has anti-cachexic activity by binding to GDF15 to prevent its binding to GFRAL, thus disrupting GDF15/GFRAL mediated signaling. Ponsegromab has potential anticancer activity and can be used to treat cancer patients with cancer anorexia cachexia syndrome.
靶点活性	GDF15:0.1095 μg/mL (EC50), GDF15-GFRAL:0.5037 μg/mL
别名	PF 06946860

化学信息

分子量	146.08 kDa
CAS No.	2368950-15-4

储存&溶解度

存储	store at low temperature \| Pure form: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.