Vitronectin Protein, Human, Recombinant (Truncated, His)

Vitronectin, also known as VTN, is a large glycoprotein found in blood and the extracellular matrix (ECM). Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood coagulation, fibrinolysis, pericellular proteolysis, complement dependent immune responses, and cell attachment and spreading. Blocking of Hic(a member of the pneumococcal surface protein C (PspC) family) by specific antiserum or genetic deletion significantly reduced pneumococcal binding to soluble and immobilised vitronectin and to Factor H, respectively. In addition, Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.

规格	价格/CNY		数量
10 μg	￥ 150	5日内发货
50 μg	￥ 500	5日内发货
500 μg	￥ 1,770	5日内发货
1 mg	￥ 2,660	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 150

5日内发货

50 μg

￥ 500

5日内发货

500 μg

￥ 1,770

5日内发货

1 mg

￥ 2,660

5日内发货

产品描述

种属	Human
表达系统	HEK293 Cells
标签	C-6xHis
蛋白编号	AAH05046.1
别名	Vitronectin, Complement S-protein, Serum Spreading Factor, epibolin, Somatomedin B, Serum-spreading factor, S-protein, V75, VN, VTN, VNT
氨基酸序列	Val62-Leu478
蛋白构建	Val62-Leu478
蛋白纯度	Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
分子量	60-70 KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris HCl, 150 mM NaCl, 0.02% Tween 80, pH8.0.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Vitronectin, also known as VTN, is a large glycoprotein found in blood and the extracellular matrix (ECM). Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood coagulation, fibrinolysis, pericellular proteolysis, complement dependent immune responses, and cell attachment and spreading. Blocking of Hic(a member of the pneumococcal surface protein C (PspC) family) by specific antiserum or genetic deletion significantly reduced pneumococcal binding to soluble and immobilised vitronectin and to Factor H, respectively. In addition, Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.

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Vitronectin Protein, Human, Recombinant (Truncated, His)

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