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Anti-delta 2 Catenin Antibody (8O145)

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货号 TMAB-05071

Anti-delta 2 Catenin Antibody (8O145) 是一种 Rabbit 抗体,靶向 delta 2 Catenin。Anti-delta 2 Catenin Antibody (8O145) 可用于 WB, ICC/IF, FCM。

Anti-delta 2 Catenin Antibody (8O145)

Anti-delta 2 Catenin Antibody (8O145)

一键复制产品信息
Rating icon 还可以
货号 TMAB-05071

Anti-delta 2 Catenin Antibody (8O145) 是一种 Rabbit 抗体,靶向 delta 2 Catenin。Anti-delta 2 Catenin Antibody (8O145) 可用于 WB, ICC/IF, FCM。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-delta 2 Catenin Antibody (8O145) is a Rabbit antibody targeting delta 2 Catenin. Anti-delta 2 Catenin Antibody (8O145) can be used in WB, ICC/IF, FCM.
Ig Type
IgG
克隆号
8O145
反应种属
Mouse,Rat,Human
验证活性
1. The SH-SY5Y (H) cells were fixed with 4% PFA (10 min at r. T.) and then permeabilized with 90% ice-cold methanol for 20 min at -20℃, the cells then were incubated in 5% BSA to block non-specific protein-protein interactions (30 min at r. T.), followed by secondary antibody incubation for 40 min at room temperature. Primary Antibody (green): Rabbit Anti-delta 2 Catenin antibody (TMAB-05071, 1: 100); Isotype Control (orange): Rabbit IgG. Blank control (black): PBS. Acquisition of 20,000 events was performed.
2. 25 ug total protein per lane of various lysates (see on figure) probed with delta 2 Catenin monoclonal antibody, unconjugated (TMAB-05071) at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
应用WBICC/IFFCM
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Predominantly expressed in brain.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Has a critical role in neuronal development, particularly in the formation and/or maintenance of dendritic spines and synapses. Involved in the regulation of canonical Wnt signaling.It probably acts on beta-catenin turnover, facilitating beta-catenin interaction with GSK3B, phosphorylation, ubiquitination and degradation.
抗原信息
免疫原
A synthesized peptide: mouse delta 2 Catenin
抗原种属
Mouse
基因名称
CTNND2
基因ID
蛋白名称
Catenin delta-2
Uniprot ID
功能
Functions as a transcriptional activator when bound to ZBTB33 (By similarity). May be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules.
化学信息
分子量Theoretical: 135 kDa. Actual: 135 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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