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Anti-beta Adducin Polyclonal Antibody

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货号 TMAB-03095

Anti-beta Adducin Polyclonal Antibody 是一种 Rabbit 抗体,靶向 beta Adducin。Anti-beta Adducin Polyclonal Antibody 可用于 WB。

Anti-beta Adducin Polyclonal Antibody

Anti-beta Adducin Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-03095

Anti-beta Adducin Polyclonal Antibody 是一种 Rabbit 抗体,靶向 beta Adducin。Anti-beta Adducin Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-beta Adducin Polyclonal Antibody is a Rabbit antibody targeting beta Adducin. Anti-beta Adducin Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Rat
验证活性
25 μg total protein per lane of various lysates (see on figure) probed with beta Adducin polyclonal antibody, unconjugated (TMAB-03095) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane-cytoskeleton-associated protein.
组织特异性Expressed mainly in brain, spleen, kidney cortex and medulla, and heart. Also expressed in human umbilical vein endothelial cells, human vascular smooth muscle cells, kidney tubular cells and K-562 cell line.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha and beta adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha and gamma adducins are ubiquitously expressed. In contrast, beta adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca2+/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
抗原信息
免疫原
KLH conjugated synthetic peptide: human beta Adducin protein
抗原种属
Human
基因名称
ADD2
基因ID
蛋白名称
beta-adducin
Uniprot ID
功能
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit.
化学信息
分子量Theoretical: 80 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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