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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CSP Polyclonal Antibody

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货号 TMAB-04732

Anti-CSP Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CSP。Anti-CSP Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-CSP Polyclonal Antibody

Anti-CSP Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04732

Anti-CSP Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CSP。Anti-CSP Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-CSP Polyclonal Antibody is a Rabbit antibody targeting CSP. Anti-CSP Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Pig,Cow,Horse,Rabbit,Sheep,GuineaPig)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
组织特异性Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain and heart.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Cysteine string proteins (CSPs) are synaptic vesicle-associated, secretory vesicle proteins that are involved in Ca2+-regulated exocytosis of synaptic vesicles and modulation of presynaptic transmembrane calcium fluxes in neuroendocrine and endocrine cell types. CSP contains a J-domain that binds HSP 70/HSC 70 chaperone ATPases and a membrane-targeting, palmitoylated cysteine-rich string region. CSPs may act as molecular chaperones in synapses, and mediate conformational folding of components of the vesicular exocytotic machinery. CSP is involved in the fine tuning of neurotransmission through its interaction with receptor-coupled trimeric GTP binding proteins (G proteins) and N-type Ca2+ channels. Two variants of CSP have been described: CSP1; and the 31 amino acid, C-terminally truncated isoform, CSP2. Subcellular fractionation of insulinoma cells shows CSP1 in granular fractions, while the membrane and cytosol fractions contain predominantly CSP2. The fractions also contain additional proteins, presumably CSP dimers. Furthermore, in various mammalian cell lines (including rat brain) CSP1 expression predominates CSP2 expression.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CSP
抗原种属
Human
基因名称
DNAJC5
基因ID
80331
蛋白名称
DnaJ homolog subfamily C member 5
Uniprot ID
Q9H3Z4
功能
May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings.
化学信息
分子量Theoretical: 22 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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