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Anti-AGRP Antibody (3R312) 是一种 Mouse 抗体,靶向 AGRP。Anti-AGRP Antibody (3R312) 可用于 ELISA。
Anti-AGRP Antibody (3R312) 是一种 Mouse 抗体,靶向 AGRP。Anti-AGRP Antibody (3R312) 可用于 ELISA。
产品描述 | Anti-AGRP Antibody (3R312) is a Mouse antibody targeting AGRP. Anti-AGRP Antibody (3R312) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG2a |
克隆号 | 3R312 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human AGRP (rh AGRP; NP_001129.1Ser85-Thr132). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Agouti Related Protein (AGRP, or AGRT), is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. AGRP can act as a competitive antagonist to proopiomelanocortin (POMC)-derived peptides at the melanocortin-4 receptor (MC4R), and that this homeostatic mechanism is important as a means of coordinating appetite with perceived metabolic requirement. AGRP is upregulated by fasting while intracerebroventricular injections of synthetic AGRP lead to increased appetite and food intake. Thus, AGRP is a powerful orexigenic peptide that increases food intake when ubiquitously overexpressed or when administered centrally. |
偶联 | Unconjugated |
免疫原 | Recombinant Human AGRP Protein |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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