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Anti-Leukotriene A4 Hydrolase Antibody (2M416)

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Anti-Leukotriene A4 Hydrolase Antibody (2M416)
产品编号 TMAY-00546
别名 Lta4h, leukotriene A4 hydrolase

Anti-Leukotriene A4 Hydrolase Antibody (2M416) 是一种 Rabbit 抗体,靶向 Leukotriene A4 Hydrolase。Anti-Leukotriene A4 Hydrolase Antibody (2M416) 可用于 ELISA。

Anti-Leukotriene A4 Hydrolase Antibody (2M416)

Anti-Leukotriene A4 Hydrolase Antibody (2M416)

Rating icon 还可以
Anti-Leukotriene A4 Hydrolase Antibody (2M416)
产品编号 TMAY-00546 别名 Lta4h, leukotriene A4 hydrolase

Anti-Leukotriene A4 Hydrolase Antibody (2M416) 是一种 Rabbit 抗体,靶向 Leukotriene A4 Hydrolase。Anti-Leukotriene A4 Hydrolase Antibody (2M416) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-Leukotriene A4 Hydrolase Antibody (2M416) is a Rabbit antibody targeting Leukotriene A4 Hydrolase. Anti-Leukotriene A4 Hydrolase Antibody (2M416) can be used in ELISA.
别名Lta4h, leukotriene A4 hydrolase
Ig Type
Rabbit IgG
克隆号
2M416
交叉反应
Human
应用
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human Leukotriene A4 Hydrolase / LTA4H (rh Leukotriene A4 Hydrolase / LTA4H; TMPY-00877; NP_000886.1; Met 1-Asp 611).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Leukotriene A-4 hydrolase, also known as LTA-4 hydrolase, Leukotriene A (4) hydrolase, LTA4H, and LTA4, is a cytoplasm protein that belongs to the peptidase M1 family. LTA4H hydrolyzes an epoxide moiety of leukotriene A4 (LTA-4) to form leukotriene B4 (LTB-4). This enzyme also has some peptidase activity. The leukotrienes (LTs) are a class of structurally related lipid mediators involved in the development and maintenance of inflammatory and allergic reactions. In the biosynthesis of LTs, arachidonic acid was converted into the unstable intermediate epoxide LTA4, which may, in turn, be conjugated with glutathione to form the spasmogenic LTC4, or hydrolyzed into the pro-inflammatory lipid mediator LTB4 in a reaction catalyzed by Leukotriene A4 hydrolase (LTA4H). LTB4 is a classical chemoattractant of human neutrophils and triggers adherence and aggregation of leukocytes to vascular endothelium, and also modulates immune responses. As a bifunctional zinc metalloenzyme, LTA4H also exhibits an anion-dependant arginyl aminopeptidase activity of high efficiency and specificity in addition to its epoxide hydrolase activity. LTA4H is regarded as a therapeutic target for inflammation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human Leukotriene A4 Hydrolase / LTA4H protein (TMPY-00877)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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