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Anti-Leukotriene A4 Hydrolase Antibody (2M416)
还可以产品编号 TMAY-00546
Anti-Leukotriene A4 Hydrolase Antibody (2M416) 是一种 Rabbit 抗体，靶向 Leukotriene A4 Hydrolase。Anti-Leukotriene A4 Hydrolase Antibody (2M416) 可用于 ELISA。
Anti-Leukotriene A4 Hydrolase Antibody (2M416)
Anti-Leukotriene A4 Hydrolase Antibody (2M416)
还可以产品编号 TMAY-00546
Anti-Leukotriene A4 Hydrolase Antibody (2M416) 是一种 Rabbit 抗体，靶向 Leukotriene A4 Hydrolase。Anti-Leukotriene A4 Hydrolase Antibody (2M416) 可用于 ELISA。
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偶联与修饰
抗原信息
| 产品描述 | Anti-Leukotriene A4 Hydrolase Antibody (2M416) is a Rabbit antibody targeting Leukotriene A4 Hydrolase. Anti-Leukotriene A4 Hydrolase Antibody (2M416) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 2M416 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Leukotriene A4 Hydrolase / LTA4H (rh Leukotriene A4 Hydrolase / LTA4H; TMPY-00877; NP_000886.1; Met 1-Asp 611). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Leukotriene A-4 hydrolase, also known as LTA-4 hydrolase, Leukotriene A (4) hydrolase, LTA4H, and LTA4, is a cytoplasm protein that belongs to the peptidase M1 family. LTA4H hydrolyzes an epoxide moiety of leukotriene A4 (LTA-4) to form leukotriene B4 (LTB-4). This enzyme also has some peptidase activity. The leukotrienes (LTs) are a class of structurally related lipid mediators involved in the development and maintenance of inflammatory and allergic reactions. In the biosynthesis of LTs, arachidonic acid was converted into the unstable intermediate epoxide LTA4, which may, in turn, be conjugated with glutathione to form the spasmogenic LTC4, or hydrolyzed into the pro-inflammatory lipid mediator LTB4 in a reaction catalyzed by Leukotriene A4 hydrolase (LTA4H). LTB4 is a classical chemoattractant of human neutrophils and triggers adherence and aggregation of leukocytes to vascular endothelium, and also modulates immune responses. As a bifunctional zinc metalloenzyme, LTA4H also exhibits an anion-dependant arginyl aminopeptidase activity of high efficiency and specificity in addition to its epoxide hydrolase activity. LTA4H is regarded as a therapeutic target for inflammation. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Leukotriene A4 Hydrolase / LTA4H protein (TMPY-00877) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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