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Anti-RP105/CD180 Antibody (7P240)

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产品编号 TMAY-03323

Anti-RP105/CD180 Antibody (7P240) 是一种 Rabbit 抗体,靶向 RP105/CD180。Anti-RP105/CD180 Antibody (7P240) 可用于 ELISA,IHC-P。

Anti-RP105/CD180 Antibody (7P240)

Anti-RP105/CD180 Antibody (7P240)

Rating icon 还可以
产品编号 TMAY-03323

Anti-RP105/CD180 Antibody (7P240) 是一种 Rabbit 抗体,靶向 RP105/CD180。Anti-RP105/CD180 Antibody (7P240) 可用于 ELISA,IHC-P。

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产品介绍

生物活性
产品描述
Anti-RP105/CD180 Antibody (7P240) is a Rabbit antibody targeting RP105/CD180. Anti-RP105/CD180 Antibody (7P240) can be used in ELISA,IHC-P.
Ig Type
Monoclonal Rabbit IgG
克隆号
7P240
交叉反应
Mouse
验证活性
1. Immunochemical staining of mouse CD180 in mouse thymus with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections).

2. Immunochemical staining of mouse CD180 in mouse spleen with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections).
应用
ELISA,IHC-P
推荐剂量
ELISA: 1:5000-1:10000; IHC-P: 1:50-1:200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD180 / RP105 (rM CD180 / RP105; TMPY-01667; NP_032559.2; Met1-Ser626).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD180, also known as RP105, is a B-cell surface molecule belonging to the family of pathogen receptors, Toll-like receptors (TLR). CD180 has an extracellular leucine-rich repeats and a short cytoplasmic tail. CD180 / RP105 interacts with an extracellular molecule named MD1 and then together form the cell surface receptor complex RP105 / MD1 which induces B-cell activation in humans and mice, leading to proliferation and up-regulation of a costimulatory molecule, B7.2 / CD86. CD180 / RP105 also has a role in LPS response because B cells lacking RP105 show hyporesponsiveness to LPS.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Mouse CD180 / RP105 Protein (TMPY-01667)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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