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Anti-CD46 Antibody (3J800)
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产品编号 TMAC-00720
别名 Trophoblast leukocyte common antigen, TLX, Membrane cofactor protein
Anti-CD46 Antibody (3J800) 是一种 Rabbit 抗体，靶向 CD46。Anti-CD46 Antibody (3J800) 可用于 WB,ICC,IHC。
Anti-CD46 Antibody (3J800)
Anti-CD46 Antibody (3J800)
还可以产品编号 TMAC-00720 别名 Trophoblast leukocyte common antigen, TLX, Membrane cofactor protein
Anti-CD46 Antibody (3J800) 是一种 Rabbit 抗体，靶向 CD46。Anti-CD46 Antibody (3J800) 可用于 WB,ICC,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,480 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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抗原信息
化学信息
| 产品描述 | Anti-CD46 Antibody (3J800) is a Rabbit antibody targeting CD46. Anti-CD46 Antibody (3J800) can be used in WB,ICC,IHC. |
| 别名 | Trophoblast leukocyte common antigen, TLX, Membrane cofactor protein |
| Ig Type | IgG |
| 克隆号 | 3J800 |
| 交叉反应 | Human,Rat |
| 验证活性 | 1. Western blot analysis of CD46 on Siha and PC-3M cell lysates using anti-CD46 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-CD46 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-CD46 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-CD46 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-CD46 antibody. Counter stained with hematoxylin. 6. ICC staining CD46 in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. ICC staining CD46 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-5000; IHC: 1:50-200; ICC: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | CD46, also called membrane cofactor protein (MCP), is a transmembrane glycoprotein that exists as a non-disulfide-linked dimer. CD46 regulates the complement cascade by inhibiting C3b and C4b deposited on self tissue. CD46 is a cofactor that binds to C3b and C4b, allowing their degradation by a plasma serine protease called factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is widely distributed on thymocytes, T cells, B cells, monocytes, granulocytes, NK cells, platelets, endothelial cells, epithelial cells, fibroblasts, placenta and sperm, but not on erythrocytes. It is the major high affinity receptor for measles virus and human herpes virus. Mouse cells ubiquitously express CRRY, which is a functional ortholog of human decay-accelerating factor (DAF; CD55) and membrane cofactor protein (MCP; CD46). |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 55 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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