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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-LC3B Antibody (7R171)

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货号 TMAB-08239

Anti-LC3B Antibody (7R171) 是一种 Rabbit 抗体，靶向 LC3B。Anti-LC3B Antibody (7R171) 可用于 IHC-P,IHC-Fr,IF,WB。

Anti-LC3B Antibody (7R171)

Anti-LC3B Antibody (7R171)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08239

Anti-LC3B Antibody (7R171) 是一种 Rabbit 抗体，靶向 LC3B。Anti-LC3B Antibody (7R171) 可用于 IHC-P,IHC-Fr,IF,WB。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-LC3B Antibody (7R171) is a Rabbit antibody targeting LC3B. Anti-LC3B Antibody (7R171) can be used in IHC-P,IHC-Fr,IF,WB.
Ig Type
IgG/Kappa
克隆号
7R171
反应种属
Human,Mouse,Rat
应用IHC-PIHC-FrIFWB
推荐剂量
IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200; WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note: LC3B binds to the autophagic membranes.
组织特异性Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. LC3, a ubiquitin-like modifier protein, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. LC3 is expressed as 3 splice variants (LC3A, LC3B and LC3C), which exhibit different tissue distributions and are processed into cytosolic and autophagosomal membrane-bound forms, termed LC3-I and LC3-II, respectively. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies, where LC3 is widely employed as a marker for autophagy.
抗原信息
免疫原
A synthesized peptide: human LC3B
抗原种属
Human
基因名称
MAP1LC3B
基因ID
81631
蛋白名称
Microtubule-associated proteins 1A/1B light chain 3B
Uniprot ID
Q9GZQ8
功能
Probably involved in formation of autophagosomal vacuoles (autophagosomes).
化学信息
分子量Theoretical: 15 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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