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Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-ALK (Tyr1096)。Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody 可用于 IHC。
Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-ALK (Tyr1096)。Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody 可用于 IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,235 | 5日内发货 |
产品描述 | Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ALK (Tyr1096). Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody can be used in IHC. |
别名 | p-ALK (Y1096), p-ALK (Tyr1096), ALK (p-Y1096), ALK (p-Tyr1096) |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human brain tissue, using ALK (Phospho-Tyr1096) antibody TMAC-00140 (left)or the same antibody preincubated with blocking peptide (right). |
应用 | |
推荐剂量 | IHC: 1:50-100 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | The 2;5 chromosomal translocation is frequently associated with anaplastic large cell lymphomas (ALCLs). The translocation creates a fusion gene consisting of the ALK (anaplastic lymphoma kinase) gene and the nucleophosmin (NPM) gene: the 3' half of ALK, derived from chromosome 2, is fused to the 5' portion of NPM from chromosome 5. A recent study shows that the product of the NPM-ALK fusion gene is oncogenic. The deduced amino acid sequences reveal that ALK is a novel receptor protein-tyrosine kinase having a putative transmembrane domain and an extracellular domain. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of tyrosine 1096 (P-N-Y(p)-C-F) derived from Human ALK |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 176 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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