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Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody

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Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody
产品编号 TMAC-00140
别名 p-ALK (Y1096), p-ALK (Tyr1096), ALK (p-Y1096), ALK (p-Tyr1096)

Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-ALK (Tyr1096)。Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody 可用于 IHC。

Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody

Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody
产品编号 TMAC-00140 别名 p-ALK (Y1096), p-ALK (Tyr1096), ALK (p-Y1096), ALK (p-Tyr1096)

Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-ALK (Tyr1096)。Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody 可用于 IHC。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,235
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ALK (Tyr1096). Anti-Phospho-ALK (Tyr1096) Polyclonal Antibody can be used in IHC.
别名p-ALK (Y1096), p-ALK (Tyr1096), ALK (p-Y1096), ALK (p-Tyr1096)
Ig Type
IgG
交叉反应
Human
验证活性
1. Immunohistochemical analysis of paraffin-embedded human brain tissue, using ALK (Phospho-Tyr1096) antibody TMAC-00140 (left)or the same antibody preincubated with blocking peptide (right).
应用
推荐剂量
IHC: 1:50-100
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景The 2;5 chromosomal translocation is frequently associated with anaplastic large cell lymphomas (ALCLs). The translocation creates a fusion gene consisting of the ALK (anaplastic lymphoma kinase) gene and the nucleophosmin (NPM) gene: the 3' half of ALK, derived from chromosome 2, is fused to the 5' portion of NPM from chromosome 5. A recent study shows that the product of the NPM-ALK fusion gene is oncogenic. The deduced amino acid sequences reveal that ALK is a novel receptor protein-tyrosine kinase having a putative transmembrane domain and an extracellular domain.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of tyrosine 1096 (P-N-Y(p)-C-F) derived from Human ALK
抗原种属
human
Uniprot ID
化学信息
分子量Actual: 176 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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