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Anti-IL-4 Polyclonal Antibody

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Anti-IL-4 Polyclonal Antibody
产品编号 TMAB-00961
别名 白细胞介素, interleukin 4, BSF-1

Anti-IL-4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IL-4。Anti-IL-4 Polyclonal Antibody 可用于 WB。

Anti-IL-4 Polyclonal Antibody

Anti-IL-4 Polyclonal Antibody

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Anti-IL-4 Polyclonal Antibody
产品编号 TMAB-00961 别名 白细胞介素, interleukin 4, BSF-1

Anti-IL-4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IL-4。Anti-IL-4 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-IL-4 Polyclonal Antibody is a Rabbit antibody targeting IL-4. Anti-IL-4 Polyclonal Antibody can be used in WB.
别名白细胞介素, interleukin 4, BSF-1
Ig Type
IgG
交叉反应
Mouse
验证活性
Sample:
Lane 1: Recombinant mouse IL-4 protein, His (HEK293)
Primary: Anti-IL4 (TMAB-00961) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 17 kDa
Observed band size: 17 kDa
应用
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse IL-4
抗原种属
Mouse
基因名称
IL4
基因ID
蛋白名称
Interleukin-4
Uniprot ID
研究领域
Interleukins,Regulatory T Cells,Interleukins
功能
Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
化学信息
分子量Theoretical: 14 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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