购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NKX6.1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-09512

Anti-NKX6.1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NKX6.1。Anti-NKX6.1 Polyclonal Antibody 可用于 WB。

Anti-NKX6.1 Polyclonal Antibody

Anti-NKX6.1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-09512

Anti-NKX6.1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NKX6.1。Anti-NKX6.1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-NKX6.1 Polyclonal Antibody is a Rabbit antibody targeting NKX6.1. Anti-NKX6.1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Pancreatic beta cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Members of the Nkx family of homeodomain proteins are key regulators of growth and development in several tissues, including brain, heart and pancreas. During neural development, sonic hedgehog (Shh) is known to control cell fate and mitogenesis, which is correlated with Shh dose-dependent expression of several genes, including Nkx-6.1. Specifically, Nkx-6.1 is responsible for cellular differentiation in the ventral neural tube and spinal meninges in response to Shh. In the pancreas, Nkx-6.1 is exclusively expressed in the islets of Langerhans in differentiating and mature b cells, which produce insulin. The presence of Pdx-1 is required for the expression of Nkx-6.1 as well as other pancreatic b cell specific genes, including insulin, Glut2 and IAPP. Subsequently, Nkx-6.1 binds to the DNA consensus sequence, TTAATTAC, to direct the repression of specific genes in b cells.
抗原信息
免疫原
KLH conjugated synthetic peptide: Human NKX6.1
抗原种属
Human
基因名称
NKX6-1
基因ID
4825
蛋白名称
Homeobox protein Nkx-6.1
Uniprot ID
P78426
功能
Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in transcriptional regulation in islet beta cells. Binds to the insulin promoter and is involved in regulation of the insulin gene. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals.
化学信息
分子量Theoretical: 38 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
Related Tags: buy Anti-NKX6.1 Polyclonal Antibody | purchase Anti-NKX6.1 Polyclonal Antibody | Anti-NKX6.1 Polyclonal Antibody cost | order Anti-NKX6.1 Polyclonal Antibody | Anti-NKX6.1 Polyclonal Antibody molecular weight