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顶部生物活性储存和溶解信息计算器

Anti-VE-Cadherin Antibody (6P223)

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产品编号 TMAY-03165

别名 cadherin 5, type 2 (vascular endothelium)

Anti-VE-Cadherin Antibody (6P223) 是一种 Rabbit 抗体，靶向 VE-Cadherin。Anti-VE-Cadherin Antibody (6P223) 可用于 FCM。

Anti-VE-Cadherin Antibody (6P223)

Anti-VE-Cadherin Antibody (6P223)

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Rating icon 还可以
产品编号 TMAY-03165 别名 cadherin 5, type 2 (vascular endothelium)

Anti-VE-Cadherin Antibody (6P223) 是一种 Rabbit 抗体，靶向 VE-Cadherin。Anti-VE-Cadherin Antibody (6P223) 可用于 FCM。

规格价格库存数量
100 μL
¥ 2,289
5日内发货
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产品介绍

生物活性
产品描述
Anti-VE-Cadherin Antibody (6P223) is a Rabbit antibody targeting VE-Cadherin. Anti-VE-Cadherin Antibody (6P223) can be used in FCM.
别名cadherin 5, type 2 (vascular endothelium)
Ig Type
Rabbit IgG
克隆号
6P223
交叉反应
Mouse
特异性
Mouse VE-Cadherin
验证活性
Flow cytometric analysis of Mouse CDH5(CD144) expression on bEnd.3 cells. Cells were stained with purified anti-Mouse CDH5(CD144), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用FCM
推荐剂量
FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse VE-Cadherin / CD144 / CDH5 (rM VE-Cadherin / CD144 / CDH5; TMPY-01237; NP_033998.2; Met1-Ala592).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Cadherins (Calcium dependent adhesion molecules) are a class of transmembrane proteins. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in the formation, maturation and remodeling of the vascular wall. VE-Cadherin is widely considered to be specific for vascular endothelia in which it is either the sole or the predominant cadherin, often co-existing with N-cadherin. This specificity of VE-cadherin for vascular endothelial cells is important not only in blood and lymph vessel biology and medicine, but also for cell-type-based diagnoses, notably those of metastatic tumors. As a classical cadherin, VE-Cadherin links endothelial cells together by homophilic interactions mediated by its extracellular part and associates intracellularly with the actin cytoskeleton via catenins. Mechanisms that regulate VE-cadherin-mediated adhesion are important for the control of vascular permeability and leukocyte extravasation. In addition to its adhesive functions, VE-Cadherin regulates various cellular processes such as cell proliferation and apoptosis and modulates vascular endothelial growth factor receptor functions. Consequently, VE-cadherin is essential during embryonic angiogenesis.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
APC/PE
可提供抗体种类
3
抗原信息
免疫原
Recombinant Protein: Mouse VE-Cadherin / CD144 / CDH5 Protein (TMPY-01237)
抗原种属
Mouse
研究领域
Hemangioblast Markers, Cardiac Stem Cell Markers
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

vascular endotheliumcadherin 5, type 2

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