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Anti-OSMR Antibody-APC (5Q467)

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Anti-OSMR Antibody-APC (5Q467)
产品编号 TMAY-01775A
别名 OSMRB, oncostatin M receptor

Anti-OSMR Antibody-APC (5Q467) 是一种 APC-conjugated Rabbit 抗体，靶向 OSMR。Anti-OSMR Antibody-APC (5Q467) 可用于 FCM。

Anti-OSMR Antibody-APC (5Q467)
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Anti-OSMR Antibody-APC (5Q467)

Rating icon 还可以
Anti-OSMR Antibody-APC (5Q467)
产品编号 TMAY-01775A 别名 OSMRB, oncostatin M receptor

Anti-OSMR Antibody-APC (5Q467) 是一种 APC-conjugated Rabbit 抗体，靶向 OSMR。Anti-OSMR Antibody-APC (5Q467) 可用于 FCM。

规格价格库存数量
25 T
¥ 1,080
5日内发货
100 T
¥ 2,180
5日内发货
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产品介绍

生物活性
产品描述
Anti-OSMR Antibody-APC (5Q467) is a APC-conjugated Rabbit antibody targeting OSMR. Anti-OSMR Antibody-APC (5Q467) can be used in FCM.
别名OSMRB, oncostatin M receptor
Ig Type
Rabbit IgG
克隆号
5Q467
交叉反应
Human
验证活性
Flow cytometric analysis of Human OSMR expression in HeLa cells.
应用
FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human OSMR / IL-31RB (rh OSMR / IL-31RB; TMPY-01305; NP_003990.1; Met1-Met740) and conjugated with APC under optimum conditions, the unreacted APC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景Oncostatin-M specific receptor subunit beta also known as the oncostatin M receptor (OSMR) and Interleukin-31 receptor subunit beta (IL-31RB), is one of the receptor proteins for oncostatin M. OSMR is a member of the type I cytokine receptor family. IL-31RB/OSMR heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in IL-31RB/OSMR have been associated with familial primary localized cutaneous amyloidosis. Defects in IL-31RB/OSMR are the cause of amyloidosis primary localized cutaneous type 1 (PLCA1), also known as familial lichen amyloidosis of familial cutaneous lichen amyloidosis. PLCA1 is hereditary primary amyloidosis characterized by localized cutaneous amyloid deposition. This condition usually presents with itching (especially on the lower legs) and visible changes of skin hyperpigmentation and thickening (lichenification) that may be exacerbated by chronic scratching and rubbing. The amyloid deposits probably reflect a combination of degenerate keratin filaments, serum amyloid P component, and deposition of immunoglobulins.
偶联与修饰
偶联
APC
其他可选修饰符
Unconjugated/PE
可提供抗体种类
3
抗原信息
免疫原
Recombinant Protein: Human OSMR / IL-31RB protein (TMPY-01305)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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