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Anti-MIA40 Polyclonal Antibody

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货号 TMAB-08805

Anti-MIA40 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MIA40。Anti-MIA40 Polyclonal Antibody 可用于 WB。

Anti-MIA40 Polyclonal Antibody

Anti-MIA40 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08805

Anti-MIA40 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MIA40。Anti-MIA40 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-MIA40 Polyclonal Antibody is a Rabbit antibody targeting MIA40. Anti-MIA40 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion intermembrane space.
组织特异性Expressed in all tissues tested, suggesting an ubiquitous expression.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景CHCHD4, a component of human mitochondria, belongs to a protein family whose members share 6 highly conserved cysteine residues constituting a -CXC-CX(9)C-CX(9)C- motif in the C terminus (Hofmann et al., 2005 [PubMed 16185709]).[supplied by OMIM, Mar 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human MIA40
抗原种属
Human
基因名称
CHCHD4
基因ID
蛋白名称
Mitochondrial intermembrane space import and assembly protein 40
Uniprot ID
功能
Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Probably acts by forming a redox cycle with GFER/ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS.
化学信息
分子量Theoretical: 16 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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