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Anti-SUZ12 Antibody (5A460)
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产品编号 TMAC-03924
别名 Suppressor of zeste 12 protein homolog, Polycomb protein SUZ12, KIAA0160, Joined to JAZF1 protein, JJAZ1, Chromatin precipitated E2F target 9 protein, CHET9, ChET 9 protein
Anti-SUZ12 Antibody (5A460) 是一种 Rabbit 抗体，靶向 SUZ12。Anti-SUZ12 Antibody (5A460) 可用于 WB,ICC/IF,IP。
Anti-SUZ12 Antibody (5A460)
Anti-SUZ12 Antibody (5A460)
还可以产品编号 TMAC-03924 别名 Suppressor of zeste 12 protein homolog, Polycomb protein SUZ12, KIAA0160, Joined to JAZF1 protein, JJAZ1, Chromatin precipitated E2F target 9 protein, CHET9, ChET 9 protein
Anti-SUZ12 Antibody (5A460) 是一种 Rabbit 抗体，靶向 SUZ12。Anti-SUZ12 Antibody (5A460) 可用于 WB,ICC/IF,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
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产品介绍
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偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-SUZ12 Antibody (5A460) is a Rabbit antibody targeting SUZ12. Anti-SUZ12 Antibody (5A460) can be used in WB,ICC/IF,IP. |
| 别名 | Suppressor of zeste 12 protein homolog, Polycomb protein SUZ12, KIAA0160, Joined to JAZF1 protein, JJAZ1, Chromatin precipitated E2F target 9 protein, CHET9, ChET 9 protein |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of SUZ12 on MCF-7 cells lysates using anti-SUZ12 antibody at 1/1,000 dilution. 2. ICC staining SUZ12 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining SUZ12 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining SUZ12 in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining SUZ12 in SKOV-3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000; ICC/IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The Polycomb group (PcG) genes contribute to the maintenance of cell identity, cell cycle regulation and oncogenesis. The mammalian PcG proteins are regulatory proteins important for Hox gene expression, axial skeleton development and the control of proliferation and survival of hematopoietic cells. By inducing changes in chromatin structure, the PcG proteins are part of a cellular memory system that is responsible for gene activity being inherited to progeny cells. PcG proteins silence gene expression through the formation of multimeric protein complexes with different compositions. Manipulating the expression-levels of various PcG proteins in mammalian cell lines results in cellular transformation, which may be a link between the chromatin-associated PcG proteins and cancer. Polycomb protein SUZ12, also designated ChET 9 protein or joined-to-JAZF1 protein, is a nuclear protein belonging to the VEFS (VRN2-EMF2-FIS2-SUZ12) family. SUZ12 has been detected at the breakpoints of a certain recurrent chromosomal translocation which has been reported in endometrial stromal sarcoma. It is a component of the PRC2 complex, composed of EED, EZH2, SUZ12/JJAZ1, RBBP4 and RBBP7. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 83 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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