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Anti-GIMAP5 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GIMAP5。Anti-GIMAP5 Polyclonal Antibody 可用于 WB。
Anti-GIMAP5 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GIMAP5。Anti-GIMAP5 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-GIMAP5 Polyclonal Antibody is a Rabbit antibody targeting GIMAP5. Anti-GIMAP5 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Mitochondrion outer membrane; Single-pass type IV membrane protein (By similarity). Lysosome. |
| 组织特异性 | Widely expressed with high levels in lymph node and spleen. High expression found in CD4 and CD8-positive T-cells and monocytes with very low levels in B-lymphocytes. Highly expressed in B-lymphocyte-derived neoplasms. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | GIMAP5, also known as IAN5, IAN4L1 (immunity-associated nucleotide 4-like 1 protein), IAN4, IMAP3, HIMAP3 or IROD, is a 307 amino acid single-pass type IV membrane protein of the mitochondrial outer membrane. A member of the GTP-binding superfamily and the immuno-associated nucleotide (IAN) subfamily, GIMAP5 plays a role in T-cell survival and mitochondrial integrity. GIMAP5 is highly expressed in CD4 and CD8-positive T-cells and monocytes, as well as B-lymphocyte-derived neoplasms. GIMAP5 exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 7q36.1. Defects in the GIMAP5 gene are associated with systemic lupus erythematosus. |
| 免疫原 | KLH conjugated synthetic peptide: human GIMAP5 |
| 抗原种属 | Human |
| 基因名称 | GIMAP5 |
| 基因ID | |
| 蛋白名称 | GTPase IMAP family member 5 |
| Uniprot ID | |
| 功能 | Required for mitochondrial integrity and T-cell survival. May contribute to T-cell quiescence (By similarity). |
| 分子量 | Theoretical: 35 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |