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Anti-EPCR Antibody (4A726)
还可以产品编号 TMAY-02559
Anti-EPCR Antibody (4A726) 是一种 Rabbit 抗体，靶向 EPCR。Anti-EPCR Antibody (4A726) 可用于 IHC-P。
Anti-EPCR Antibody (4A726)
Anti-EPCR Antibody (4A726)
还可以产品编号 TMAY-02559
Anti-EPCR Antibody (4A726) 是一种 Rabbit 抗体，靶向 EPCR。Anti-EPCR Antibody (4A726) 可用于 IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-EPCR Antibody (4A726) is a Rabbit antibody targeting EPCR. Anti-EPCR Antibody (4A726) can be used in IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 4A726 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human PROCR in human liver with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human PROCR in human kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:100-1:500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Epcr / PROCR (rh Epcr / PROCR; TMPY-02715; Q9UNN8; Met1-Thr209). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other animals after activated by binding to Endothelial protein C receptor (EPCR). Because of the EPCR is found primarily on endothelial cells (cells on the inside of blood vessels), activated protein C is found mainly near endothelial cells. Protein C is pleiotropic, with two main functions: anticoagulation and cytoprotection. Which function will be performed depending on whether or not protein C remains bind to EPCR after activated. The anticoagulation occurs when it does not. In this case, protein C functions as an anticoagulant by irreversibly proteolytically inactivating Factor Va and Factor VIIIa, turning them into Factor Vi and Factor VIIIi respectively. When still bound to EPCR, activated protein C performs its cytoprotective effects, acting on the effector substrate PAR-1, protease-activated receptor-1. To a degree, APC's anticoagulant properties are independent of its cytoprotective ones, in that expression of one pathway is not affected by the existence of the other. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Epcr / PROCR protein (TMPY-02715) |
| 抗原种属 | Human |
| 研究领域 | Serine Proteases and Regulators |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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