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Anti-Arginase 1/ARG1 Antibody (5G793)
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产品编号 TMAH-00080
别名 arginase 1, ARG1
Anti-Arginase 1/ARG1 Antibody (5G793) 是一种抗体，靶向 Arginase 1/ARG1。Anti-Arginase 1/ARG1 Antibody (5G793) 可用于 ELISA, IHC。
Anti-Arginase 1/ARG1 Antibody (5G793)
Anti-Arginase 1/ARG1 Antibody (5G793)
还可以产品编号 TMAH-00080 别名 arginase 1, ARG1
Anti-Arginase 1/ARG1 Antibody (5G793) 是一种抗体，靶向 Arginase 1/ARG1。Anti-Arginase 1/ARG1 Antibody (5G793) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,300 | 5日内发货 | |
| 100 μL | ¥ 2,190 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Arginase 1/ARG1 Antibody (5G793) is an antibody targeting Arginase 1/ARG1. Anti-Arginase 1/ARG1 Antibody (5G793) can be used in ELISA, IHC. |
| 别名 | arginase 1, ARG1 |
| Ig Type | Rabbit IgG |
| 克隆号 | 5G793 |
| 交叉反应 | Human |
| 验证活性 | IHC image of TMAH-00080 diluted at 1:50 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.71% DAB. |
| 应用 | |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cytoplasm. Cytoplasmic granule. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys. Functions in L-arginine homeostasis in nonhepatic tissues characterized by the competition between nitric oxide synthase (NOS) and arginase for the available intracellular substrate arginine. Arginine metabolism is a critical regulator of innate and adaptive immune responses. Involved in an antimicrobial effector pathway in polymorphonuclear granulocytes (PMN). Upon PMN cell death is liberated from the phagolysosome and depletes arginine in the microenvironment leading to suppressed T cell and natural killer (NK) cell proliferation and cytokine secretion. In group 2 innate lymphoid cells (ILC2s) promotes acute type 2 inflammation in the lung and is involved in optimal ILC2 proliferation but not survival. In humans, the immunological role in the monocytic/macrophage/dendritic cell (DC) lineage is unsure. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human ARG1 |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Metabolism, Signal transduction |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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