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Anti-EPX Polyclonal Antibody

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Anti-EPX Polyclonal Antibody
产品编号 TMAB-00629
别名 PERE, EPX PEN, EPP, EPO, EPER, Eosinophil peroxidase heavy chain, Eosinophil peroxidase

Anti-EPX Polyclonal Antibody 是一种 Rabbit 抗体，靶向 EPX。Anti-EPX Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-EPX Polyclonal Antibody

Anti-EPX Polyclonal Antibody

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Anti-EPX Polyclonal Antibody
产品编号 TMAB-00629 别名 PERE, EPX PEN, EPP, EPO, EPER, Eosinophil peroxidase heavy chain, Eosinophil peroxidase

Anti-EPX Polyclonal Antibody 是一种 Rabbit 抗体，靶向 EPX。Anti-EPX Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-EPX Polyclonal Antibody is a Rabbit antibody targeting EPX. Anti-EPX Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
别名PERE, EPX PEN, EPP, EPO, EPER, Eosinophil peroxidase heavy chain, Eosinophil peroxidase
Ig Type
IgG
交叉反应
Human,Mouse (predicted:Rat)
验证活性
Tissue/cell: mouse stomach tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-EPX Polyclonal Antibody, Unconjugated (TMAB-00629) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
应用
IHC-P
IHC-Fr
IF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic granule. Note=Cytoplasmic granules of eosinophils.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景EPX, eosinophil peroxidase, is an antimycobacterial protein that localizes to cytoplasmic granules of eosinophils and recruits bromide to generate a halogenating oxidant. EPX dependent generation of hypobromous acid causes damage to tissue during inflammatory conditions that include asthma, allergies,cancer and parasitic/helminthic infections. EPX is a major enzyme present in eosinophils and upon degranulation, becomes released into the airways of asthmatics. As a result of its cationic nature and its ability to catalyze the formation of highly toxic oxidants, EPX can induce lung injury in a JNK dependent manner.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Eosinophil peroxidase heavy chain
抗原种属
Human
基因名称
EPX
基因ID
8288
蛋白名称
Eosinophil peroxidase
研究领域
Neutrophil Lineage,Cellular metabolic process
功能
Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis.
化学信息
分子量Theoretical: 79 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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