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ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His)
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货号 TMPK-00918
别名 Ms2, MGC134985, CD156a, Adam8, ADAM 8
A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 70.9 kDa and the accession number is P78325.
其他形式的 “ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His)”:
ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His)
一键复制产品信息 还可以SPR兼容缓冲液
货号 TMPK-00918 别名 Ms2, MGC134985, CD156a, Adam8, ADAM 8
A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 70.9 kDa and the accession number is P78325.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 343 | 6-8日内发货 | |
| 10 μg | ¥ 549 | 6-8日内发货 | |
| 20 μg | ¥ 898 | 5日内发货 | |
| 50 μg | ¥ 1,760 | 5日内发货 | |
| 100 μg | ¥ 2,960 | 5日内发货 | |
| 200 μg | ¥ 5,350 | 5日内发货 | |
| 500 μg | ¥ 11,800 | 5日内发货 |
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| 产品描述 | A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 70.9 kDa and the accession number is P78325. |
| 生物活性 | Immobilized Human ADAM8, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-ADAM8 Antibody, hFc Tag with the EC50 of 8.1ng/ml determined by ELISA. |
| 研究背景 | A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-His |
| 蛋白编号 | P78325 |
| 蛋白构建 | Ile17-Pro655 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | Ms2, MGC134985, CD156a, Adam8, ADAM 8 |
| 内毒素 | < 1 EU/μg by the LAL method. |
| 分子量 | 70.9 kDa (predicted) same as Tris-Bis PAGE result. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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