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Anti-Nudel Antibody (5F982)
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产品编号 TMAC-02900
别名 Protein Nudel, NUDEL, NudE nuclear distribution gene E homolog like 1 A. nidulans, NudE nuclear distribution gene E homolog like 1, NUDE like protein, Nuclear distribution protein nudE-like 1, Nuclear distribution protein nudE like 1, Nuclear distribution gene E like homolog 1, NDEL1_HUMAN, NDEL1, Ndel 1, Mitosin-associated protein 1, Mitosin associated protein MITAP1, Mitosin associated protein 1, MITAP1, MITAP 1, EOPA, ENDOOLIGOPEPTIDASE A, DKFZp451M0318, A. nidulans
Anti-Nudel Antibody (5F982) 是一种 Rabbit 抗体，靶向 Nudel。Anti-Nudel Antibody (5F982) 可用于 WB,IHC。
Anti-Nudel Antibody (5F982)
Anti-Nudel Antibody (5F982)
还可以产品编号 TMAC-02900 别名 Protein Nudel, NUDEL, NudE nuclear distribution gene E homolog like 1 A. nidulans, NudE nuclear distribution gene E homolog like 1, NUDE like protein, Nuclear distribution protein nudE-like 1, Nuclear distribution protein nudE like 1, Nuclear distribution gene E like homolog 1, NDEL1_HUMAN, NDEL1, Ndel 1, Mitosin-associated protein 1, Mitosin associated protein MITAP1, Mitosin associated protein 1, MITAP1, MITAP 1, EOPA, ENDOOLIGOPEPTIDASE A, DKFZp451M0318, A. nidulans
Anti-Nudel Antibody (5F982) 是一种 Rabbit 抗体，靶向 Nudel。Anti-Nudel Antibody (5F982) 可用于 WB,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,480 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
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产品介绍
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| 产品描述 | Anti-Nudel Antibody (5F982) is a Rabbit antibody targeting Nudel. Anti-Nudel Antibody (5F982) can be used in WB,IHC. |
| 别名 | Protein Nudel, NUDEL, NudE nuclear distribution gene E homolog like 1 A. nidulans, NudE nuclear distribution gene E homolog like 1, NUDE like protein, Nuclear distribution protein nudE-like 1, Nuclear distribution protein nudE like 1, Nuclear distribution gene E like homolog 1, NDEL1_HUMAN, NDEL1, Ndel 1, Mitosin-associated protein 1, Mitosin associated protein MITAP1, Mitosin associated protein 1, MITAP1, MITAP 1, EOPA, ENDOOLIGOPEPTIDASE A, DKFZp451M0318, A. nidulans |
| Ig Type | IgG |
| 克隆号 | 5F982 |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of Nudel on rat brain tissue lysate using anti-Nudel antibody at 1/2,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Nudel antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human small intestine tissue using anti-Nudel antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-Nudel antibody. Counter stained with hematoxylin. |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; IHC: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | NudE-like protein (Ndel1) is expressed in the testis, brain, heart, hypothalamus, liver, lung, spleen, and stomach, specifically in the interphase centrosome and mitotic spindle. It positively regulates minus-end directed dynein. Evidence suggests that Ndel1 interacts with LIS1 to sustain the function of dynein, thereby impacting microtubule organization, nuclear translocation, and neuronal positioning. Ndel1 is phosphorylated during mitosis and seems to tether dynactin and dynein to the mother centriole for microtubule anchoring. Loss of function of Ndel1 in the developing neocortex impairs neuronal positioning and uncouples the centrosome and nucleus. Ndel1 may also impair mitochondrial transport or function, initiating a cascade of events culminating in psychiatric illness such as lissencephaly and schizophrenia. |
| 偶联 | Unconjugated |
| Uniprot ID |
| 分子量 | Theoretical: 38 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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