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CD47 Protein, Human, Recombinant, Biotinylated

CD47 Protein, Human, Recombinant, Biotinylated

产品编号 TMPY-05191
别名: CD47 molecule, MER6, OA3, IAP

CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.

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CD47 Protein, Human, Recombinant, Biotinylated
规格 价格/CNY 货期 数量
20 μg ¥ 1,950 现货
100 μg ¥ 4,630 5日内发货
200 μg ¥ 7,910 5日内发货
500 μg ¥ 15,990 5日内发货
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产品目录号及名称: CD47 Protein, Human, Recombinant, Biotinylated (TMPY-05191)
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生物活性 Testing in progress
产品描述 CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
种属 Human
表达系统 HEK293 Cells
标签 Tag Free
蛋白编号 Q08722-3
别名 CD47 molecule, MER6, OA3, IAP
蛋白构建 The Human CD47 (NP_942088.1) (Met1-Pro139) was expressed with six amino acids (LEVLFQ) at the C-terminus. The purified protein was biotinylated in vitro.
蛋白纯度 > 90 % as determined by SDS-PAGE.

TargetMol

分子量 14.5 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy

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Keywords

CD47 Protein, Human, Recombinant, Biotinylated CD47 molecule OA-3 MER-6 MER 6 MER6 OA 3 OA3 IAP recombinant recombinant-proteins proteins protein

 

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