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Anti-RASA4 Polyclonal Antibody

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货号 TMAB-12104

Anti-RASA4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 RASA4。Anti-RASA4 Polyclonal Antibody 可用于 WB。

Anti-RASA4 Polyclonal Antibody

Anti-RASA4 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12104

Anti-RASA4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 RASA4。Anti-RASA4 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-RASA4 Polyclonal Antibody is a Rabbit antibody targeting RASA4. Anti-RASA4 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm; cytosol. Cell membrane; peripheral membrane protein. Note=Localized to the cytosol as a result of its lack of phosphoinositide binding activity. Upon agonist-stimulated calcium mobilization, utilizes the C2A and C2B domains to associate with the plasma membrane.
组织特异性Widely expressed.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human RASA4
抗原种属
Human
基因名称
RASA4
基因ID
蛋白名称
Ras GTPase-activating protein 4
Uniprot ID
功能
Ca2+-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulus that elevates intracellular calcium. Functions as an adaptor for Cdc42 and Rac1 during FcR-mediated phagocytosis.
化学信息
分子量Theoretical: 90 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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