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Anti-TYMS Antibody (5D281)

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货号 TMAB-13910

Anti-TYMS Antibody (5D281) 是一种 Mouse 抗体，靶向 TYMS。Anti-TYMS Antibody (5D281) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-TYMS Antibody (5D281)

Anti-TYMS Antibody (5D281)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13910

Anti-TYMS Antibody (5D281) 是一种 Mouse 抗体，靶向 TYMS。Anti-TYMS Antibody (5D281) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-TYMS Antibody (5D281) is a Mouse antibody targeting TYMS. Anti-TYMS Antibody (5D281) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG1, Kappa
克隆号
5D281
反应种属
Human
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-1000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Nucleus. Cytoplasm. Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane.
构建方式Recombinant Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occurring antisense transcript, mitochondrial enolase superfamily member 1 (GeneID:55556), vary inversely when cell-growth progresses from late-log to plateau phase. Polymorphisms in this gene may be associated with etiology of neoplasia, including breast cancer, and response to chemotherapy. [provided by RefSeq, Aug 2017]
抗原信息
基因名称
TYMS
基因ID
7298
蛋白名称
Thymidylate synthase
功能
Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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