Name: Uliledlimab
Brand: TargetMol
SKU: T76730
Price: 2570 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 2,570

现货

5 mg

¥ 5,880

现货

10 mg

¥ 7,930

现货

25 mg

¥ 11,800

现货

生物活性

产品描述	Uliledlimab is a humanized monoclonal antibody with potent inhibitory activity against CD73, the ecto-5'-nucleotidase enzyme that catalyzes the conversion of extracellular AMP to adenosine. Uliledlimab reduces extracellular adenosine production, thereby modulating immunosuppressive pathways. Uliledlimab holds significant potential for use in immuno-oncology and cancer research.
体外活性	Uliledlimab通过结合CD73蛋白的C末端结构域，完全抑制 CD73的酶活性。Uliledlimab通过阻断腺苷产生，进而解除免疫细胞抑制、提升CD8+T细胞与巨噬细胞活性，最终强化抗肿瘤免疫反应[1]。
体内活性	Uliledlimab 单独使用或与PD-L1抑制剂Atezolizumab联合使用时，能够有效抑制实体肿瘤的生长[1]。
别名	尤莱利单抗, TJ-004309, TJ004309
反应种属	Human
应用	ELISA FCM Functional assay
抗体种类	Monoclonal
内毒素	<1.0 EU/mg

抗体信息

同型	Human IgG1 kappa
推荐同型对照	Human IgG1 kappa, Isotype Control

偶联与修饰

偶联	Unconjugated

抗原信息

化学信息

储存&溶解度

存储	store at low temperature \| store at -20°C \| Shipping with blue ice/Shipping at ambient temperature.

Uliledlimab