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Anti-PDE2A Antibody (6N709) 是一种 Rabbit 抗体,靶向 PDE2A。Anti-PDE2A Antibody (6N709) 可用于 ELISA。
Anti-PDE2A Antibody (6N709) 是一种 Rabbit 抗体,靶向 PDE2A。Anti-PDE2A Antibody (6N709) 可用于 ELISA。
产品描述 | Anti-PDE2A Antibody (6N709) is a Rabbit antibody targeting PDE2A. Anti-PDE2A Antibody (6N709) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 6N709 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human PDE2A (rh PDE2A; TMPY-02081; O00408-1; Glu215-His900). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | cGMP-dependent 3',5'-cyclic phosphodiesterase, also known as cyclic GMP-stimulated phosphodiesterase and PDE2A, is a peripheral membrane protein that belongs to the cyclic nucleotide phosphodiesterase family and PDE2 subfamily. Phosphodiesterases (PDEs) comprise a family of enzymes that regulate the levels of cyclic nucleotides, key second messengers that mediate a diverse array of functions. Phosphodiesterases (PDEs) modulate signaling by cyclic nucleotides in diverse processes such as cardiac contractility, platelet aggregation, lipolysis, glycogenolysis, and smooth muscle contraction. PDE2A is an evolutionarily conserved cGMP-stimulated cAMP and cGMP PDE. PDE2A contains two GAF domains. PDE2A is expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas. PDE2A is a cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. PDE2A is involved in the regulation of blood pressure and fluid homeostasis by the atrial natriuretic peptide (ANP), making PDE2-type enzymes important targets for drug discovery. |
偶联 | Unconjugated |
免疫原 | Recombinant Human PDE2A protein (TMPY-02081) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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