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顶部产品介绍化学信息储存和溶解信息计算器

Sodium Nitrite

Synonyms: 亚硝酸钠, Nitrous acid, sodium salt
货号 T77798Cas号 7632-00-0 一键复制产品信息
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Sodium Nitrite (Nitrous acid, sodium salt) 是一种不易保存的化合物，放置在空气中会被氧化成硝酸。Sodium Nitrite 具有多种功能，既具有氧化性又具有还原性，作用颇多。

Sodium Nitrite

一键复制产品信息
Rating icon 很棒
货号 T77798Cas号 7632-00-0

别名 亚硝酸钠, Nitrous acid, sodium salt

Sodium Nitrite (Nitrous acid, sodium salt) 是一种不易保存的化合物，放置在空气中会被氧化成硝酸。Sodium Nitrite 具有多种功能，既具有氧化性又具有还原性，作用颇多。

Sodium Nitrite
其他形式的 “Sodium Nitrite”:
Sodium Nitrite (Standard)TMSM-20957632-00-0
待询
规格价格库存数量
25 mg
¥ 310
现货
50 mg
¥ 427
现货
100 mg
¥ 595
现货
500 mg
¥ 1,386
现货
1 mL x 10 mM (in DMSO)
¥ 315
现货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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该产品的销售和采购需有相关的证书文件。

实验操作小课堂
常见问题解答
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颜色: 白色
性状: Solid
资源下载: COA产品操作手册

产品介绍

Sodium Nitrite AI Summary
Sodium Nitrite demonstrates a diverse range of bioactivities across multiple biological assays. It exhibits significant in vitro activity affecting methemoglobin formation and reductase activity, inducing 100% methemoglobin formation at 1mM concentration and reducing methemoglobin levels at lower concentrations. In cancer research, it shows antiproliferative effects against the human HL60 cell line with an IC50 value of 94000.0 nM. Notably, Sodium Nitrite acts as an inhibitor for several enzymes, including Tyrosyl-DNA Phosphodiesterase (TDP1), ALDH1A1, 15-human lipoxygenase (15-hLO and 15-hLO-2), demonstrating varying potencies. It also functions as an agonist and antagonist in antioxidant response element signaling and ROR-gamma signaling pathways, respectively. The compound displays broad-spectrum antimicrobial activity, notably against Pseudomonas aeruginosa and various other bacterial strains, inhibiting both under aerobic and anaerobic conditions. Its potential for inhibiting biofilm formation has also been observed. Although it shows substantial inhibitory effects on multiple carbonic anhydrase (CA) enzymes from different species, including human CA1 and CA2, its Ki values vary widely, suggesting selective inhibition across different isoforms and organisms. Furthermore, Sodium Nitrite has shown antiviral activity against SARS-CoV-2, influencing cytotoxicity and protease functions, and demonstrates neuroprotective effects in rat cortical neuron models against OGD/R-induced apoptosis. Its binding affinity to the beta2 adrenoceptor suggests potential applications in neurological research. Overall, Sodium Nitrite's multifaceted bioactivities suggest its utility in therapeutic development across oncology, microbiology, virology, and enzyme inhibition frameworks..
Note: Summary generated by AI. Data source: ChEMBL
生物活性
产品描述
Sodium Nitrite (Nitrous acid, sodium salt) is a compound that is not easy to store and will oxidize to nitric acid if left in the air.Sodium Nitrite has a variety of functions, both oxidizing and reducing, and is very versatile.
靶点活性
E. coli:410 mg/L
别名
亚硝酸钠, Nitrous acid, sodium salt
化学信息
分子量69.00
分子式NNaO2
CAS No.7632-00-0
SmilesO=N[O-].[Na+]
储存&溶解度
存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息
H2O: 125 mg/mL (1811.59 mM), Sonication is recommended.
溶液配制表
H2O
1mg5mg10mg50mg
1 mM14.4928 mL72.4638 mL144.9275 mL724.6377 mL
5 mM2.8986 mL14.4928 mL28.9855 mL144.9275 mL
10 mM1.4493 mL7.2464 mL14.4928 mL72.4638 mL
20 mM0.7246 mL3.6232 mL7.2464 mL36.2319 mL
50 mM0.2899 mL1.4493 mL2.8986 mL14.4928 mL
100 mM0.1449 mL0.7246 mL1.4493 mL7.2464 mL
该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL， 一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O， 那么您的工作液浓度为2 mg/mL。
母液配置方法：2 mg 药物溶于 100 μL DMSO （ 母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法： 取 100 μL DMSO 母液， 添加 400 μL PEG300 混匀澄清， 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。
方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD， 玉米油等， 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

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