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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Desmocollin 3 Antibody (4M116)

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货号 TMAB-05100

Anti-Desmocollin 3 Antibody (4M116) 是一种 Rabbit 抗体，靶向 Desmocollin 3。Anti-Desmocollin 3 Antibody (4M116) 可用于 WB。

Anti-Desmocollin 3 Antibody (4M116)

Anti-Desmocollin 3 Antibody (4M116)

一键复制产品信息
Rating icon 还可以
货号 TMAB-05100

Anti-Desmocollin 3 Antibody (4M116) 是一种 Rabbit 抗体，靶向 Desmocollin 3。Anti-Desmocollin 3 Antibody (4M116) 可用于 WB。

规格价格库存数量
25 μL
¥ 790
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50 μL
¥ 1,385
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100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-Desmocollin 3 Antibody (4M116) is a Rabbit antibody targeting Desmocollin 3. Anti-Desmocollin 3 Antibody (4M116) can be used in WB.
Ig Type
IgG
克隆号
4M116
反应种属
Mouse,Rat (predicted:Human)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell membrane. Cell junction > desmosome.
组织特异性Epidermis, buccal mucosa, esophagus and cervix.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
抗原信息
免疫原
A synthesized peptide: human Desmocollin 3
抗原种属
Human
基因名称
DSC3
基因ID
1825
蛋白名称
Desmocollin-3
Uniprot ID
Q14574
功能
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
化学信息
分子量Theoretical: 100 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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