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CXCL2 Protein, Mouse, Recombinant

CXCL2 Protein, Mouse, Recombinant

产品编号 TMPJ-00011
别名: Gro-beta, GRO β, GROB, melanoma growth stimulatory activity beta, GRO2, melanoma growth stimulatory activity β, MGSA-beta, SCYB2, MIP2-α, Gro-β, chemokine ligand 2, MIP2-alpha, MGSA-b, cxcl2, Macrophage Inflammatory Protein-2-α, Growth-regulated protein β, Growth-regulated protein beta, GRO beta, MGSA-β, Macrophage Inflammatory Protein-2-alpha, MIP2A, MIP-2, C-X-C motif chemokine 2

C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The expression of mouse MIP-2 is stimulated by endotoxin. The mouse MIP-2 shares approximately 63% aa sequence identity with murine KC, another mouse alpha chemokine, which is induced by PDGF. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. The expression of MIP-2 was found to be associated with neutrophil influx in pulmonary inflammation and glomerulonephritis, suggesting that MIP-2 may contribute to the pathogenesis of inflammatory diseases.

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CXCL2 Protein, Mouse, Recombinant
规格 价格/CNY 货期 数量
10 μg ¥ 1,170 5日内发货
50 μg ¥ 3,470 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 18,900 5日内发货
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产品目录号及名称: CXCL2 Protein, Mouse, Recombinant (TMPJ-00011)
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产品描述 C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The expression of mouse MIP-2 is stimulated by endotoxin. The mouse MIP-2 shares approximately 63% aa sequence identity with murine KC, another mouse alpha chemokine, which is induced by PDGF. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. The expression of MIP-2 was found to be associated with neutrophil influx in pulmonary inflammation and glomerulonephritis, suggesting that MIP-2 may contribute to the pathogenesis of inflammatory diseases.
种属 Mouse
表达系统 E. coli
标签 Tag Free
蛋白编号 P10889
别名 Gro-beta, GRO β, GROB, melanoma growth stimulatory activity beta, GRO2, melanoma growth stimulatory activity β, MGSA-beta, SCYB2, MIP2-α, Gro-β, chemokine ligand 2, MIP2-alpha, MGSA-b, cxcl2, Macrophage Inflammatory Protein-2-α, Growth-regulated protein β, Growth-regulated protein beta, GRO beta, MGSA-β, Macrophage Inflammatory Protein-2-alpha, MIP2A, MIP-2, C-X-C motif chemokine 2
氨基酸序列 Ala28-Asn100
蛋白构建 Ala28-Asn100
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 10 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The expression of mouse MIP-2 is stimulated by endotoxin. The mouse MIP-2 shares approximately 63% aa sequence identity with murine KC, another mouse alpha chemokine, which is induced by PDGF. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. The expression of MIP-2 was found to be associated with neutrophil influx in pulmonary inflammation and glomerulonephritis, suggesting that MIP-2 may contribute to the pathogenesis of inflammatory diseases.

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Keywords

CXCL2 Protein, Mouse, Recombinant Gro-beta GRO β GROB melanoma growth stimulatory activity beta MIP2 GRO2 SCYB-2 melanoma growth stimulatory activity β GRO 2 MGSA-beta MIP 2 SCYB2 SCYB 2 MIP2-α GRO-2 Gro-β chemokine ligand 2 MIP2-alpha MGSA-b cxcl2 Macrophage Inflammatory Protein-2-α Growth-regulated protein β Growth-regulated protein beta GRO beta MGSA-β Macrophage Inflammatory Protein-2-alpha MIP2A MIP-2 C-X-C motif chemokine 2 recombinant recombinant-proteins proteins protein

 

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