购物车
- 全部删除
- 您的购物车当前为空
Anti-CD59 Antibody (9I973) 是一种 Rabbit 抗体,靶向 CD59。Anti-CD59 Antibody (9I973) 可用于 ELISA。
Anti-CD59 Antibody (9I973) 是一种 Rabbit 抗体,靶向 CD59。Anti-CD59 Antibody (9I973) 可用于 ELISA。
产品描述 | Anti-CD59 Antibody (9I973) is a Rabbit antibody targeting CD59. Anti-CD59 Antibody (9I973) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 9I973 |
交叉反应 | Rat |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Rat CD59 (rR CD59; TMPY-03091; P27274; Met1-Asn100). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | CD59 glycoprotein, also known as 2 kDa homologous restriction factor, HRF2, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membrane protein which contains one UPAR/Ly6 domain. CD59 is a small, highly glycosylated, GPI-linked protein, with a wide expression profile. The soluble form of CD59 from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. CD59 was first identified as a regulator of the terminal pathway of complement. It acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. Defects in CD59 are the cause of CD59 deficiency (CD59D). |
偶联 | Unconjugated |
免疫原 | Recombinant Rat CD59 Protein (TMPY-03091) |
抗原种属 | Rat |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
评论内容