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顶部生物活性储存和溶解信息计算器

Anti-Phospho-Ras-GRF1 (Ser916) Polyclonal Antibody

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产品编号 TMAC-03539

别名 Ras-GRF1 (p-Ser916), Ras-GRF1 (p-S916), p-Ras-GRF1 (Ser916), p-Ras-GRF1 (S916)

Anti-Phospho-Ras-GRF1 (Ser916) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Ras-GRF1 (Ser916)。Anti-Phospho-Ras-GRF1 (Ser916) Polyclonal Antibody 可用于 IHC。

Anti-Phospho-Ras-GRF1 (Ser916) Polyclonal Antibody

Anti-Phospho-Ras-GRF1 (Ser916) Polyclonal Antibody

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产品编号 TMAC-03539 别名 Ras-GRF1 (p-Ser916), Ras-GRF1 (p-S916), p-Ras-GRF1 (Ser916), p-Ras-GRF1 (S916)

Anti-Phospho-Ras-GRF1 (Ser916) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Ras-GRF1 (Ser916)。Anti-Phospho-Ras-GRF1 (Ser916) Polyclonal Antibody 可用于 IHC。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,240
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Ras-GRF1 (Ser916) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Ras-GRF1 (Ser916). Anti-Phospho-Ras-GRF1 (Ser916) Polyclonal Antibody can be used in IHC.
别名Ras-GRF1 (p-Ser916), Ras-GRF1 (p-S916), p-Ras-GRF1 (Ser916), p-Ras-GRF1 (S916)
Ig Type
IgG
交叉反应
Human,Mouse
验证活性
1. Immunohistochemical analysis of paraffin-embedded human brain tissue using Ras-GRF1 (Phospho-Ser916) antibody TMAC-03539 (left) or the same antibody preincubated with blocking peptide (right).
verifiedActivity
应用IHC
推荐剂量
IHC: 1:50-100
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Ras activity is regulated by GAP (GTPase activating proteins) and GEFs (guanine nucleotide exchange factors). Ras-GRF1 (also known as CDC25Mm) is neuronal RasGEF and is regulated by heterotrimeric G proteins and calcium influx . Binding to calmodulin and phosphorylation stimulate Ras-GRF1 activity. Multiple PKA phosphorylation sites on Ras-GRF have been identified. Phosphorylation on the two major sites, Ser54 and Ser822, inhibits Ras-GRF activity. Carbachol (a muscarinic agonist)-induced phosphorylation on Ser916 is essential but not sufficient for maximal Ras-GRF activity.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of Serine 916(R-M-S(p)-L-A) derived from Mouse Ras-GRF1
抗原种属
mouse
Uniprot ID
P27671
化学信息
分子量Actual: 145 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

Ras-GRF1 (pSer916)Ras-GRF1 (pS916)Ras-GRF1 (phospho-Ser916)Ras-GRF1 (phospho-S916)pRas-GRF1 (Ser916)pRas-GRF1 (S916)

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4个月前
5.0
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