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Anti-CD1E Polyclonal Antibody 2

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货号 TMAB-03900

Anti-CD1E Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 CD1E。Anti-CD1E Polyclonal Antibody 2 可用于 WB,FCM。

Anti-CD1E Polyclonal Antibody 2

Anti-CD1E Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-03900

Anti-CD1E Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 CD1E。Anti-CD1E Polyclonal Antibody 2 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,165
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100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

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产品描述
Anti-CD1E Polyclonal Antibody 2 is a Rabbit antibody targeting CD1E. Anti-CD1E Polyclonal Antibody 2 can be used in WB,FCM.
Ig Type
IgG
反应种属
Human
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Lysosome lumen and Golgi apparatus membrane. Early endosome. Late endosome. Predominantly localized in the trans-Golgi network in immature dendritic cells, and as a cleaved, soluble protein in the lysosome lumen of mature dendritic cells.
组织特异性Expressed on cortical thymocytes, dendritic cells, Langerhans cells, on certain T-cell leukemias, and in various other tissues
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found; however, their biological validity has not been determined. [provided by RefSeq, Jun 2010]
抗原信息
免疫原
KLH conjugated synthetic peptide: human CD1E
抗原种属
Human
基因名称
CD1E
基因ID
913
蛋白名称
T-cell surface glycoprotein CD1e, membrane-associated
Uniprot ID
P15812
功能
T-cell surface glycoprotein CD1e, soluble binds diacetylated lipids, including phosphatidyl inositides and diacylated sulfoglycolipids, and is required for the presentation of glycolipid antigens on the cell surface. The membrane-associated form is not active.
化学信息
分子量Theoretical: 42 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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