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Anti-ESAM Antibody-APC (4F225)
还可以产品编号 TMAY-00424A
Anti-ESAM Antibody-APC (4F225) 是一种 APC-conjugated Rabbit 抗体，靶向 ESAM。Anti-ESAM Antibody-APC (4F225) 可用于 FCM。
Anti-ESAM Antibody-APC (4F225)
Anti-ESAM Antibody-APC (4F225)
还可以产品编号 TMAY-00424A
Anti-ESAM Antibody-APC (4F225) 是一种 APC-conjugated Rabbit 抗体，靶向 ESAM。Anti-ESAM Antibody-APC (4F225) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-ESAM Antibody-APC (4F225) is a APC-conjugated Rabbit antibody targeting ESAM. Anti-ESAM Antibody-APC (4F225) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 4F225 |
| 交叉反应 | Human |
| 验证活性 | Profile of anti-ESAM reactivity on HUVEC cells analyzed by flow cytometry. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human ESAM (rh ESAM; TMPY-01312; NP_620411.2; Met 1-Ala 248) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | Endothelial cell-selective adhesion molecule (ESAM) is a member of JAM family of immunoglobulin superfamily and consists of one V-type and one C2-type immunoglobulin domain, as well as a hydrophobic signal sequence, a single transmembrane region, and a cytoplasmic domain. It is specifically expressed at endothelial tight junctions and on activated platelets. ESAM at endothelial tight junctions participates in the migration of neutrophils through the vessel wall, possibly by influencing endothelial cell contacts. The adaptor protein membrane-associated guanylate kinase MAGI-1 has been identified as an intracellular binding partner of ESAM. Previous studies have indicated that ESAM regulates angiogenesis in the primary tumor growth and endothelial permeability. It suggest that ESAM has a redundant functional role in physiological angiogenesis but serves a unique and essential role in pathological angiogenic processes such as tumor growth. |
| 偶联 | APC |
| 其他可选修饰符 | Unconjugated/FITC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human ESAM protein (TMPY-01312) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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