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Anti-ESAM Antibody-APC (4F225)

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Anti-ESAM Antibody-APC (4F225)
产品编号 TMAY-00424A
别名 endothelial cell adhesion molecule

Anti-ESAM Antibody-APC (4F225) 是一种 APC-conjugated Rabbit 抗体,靶向 ESAM。Anti-ESAM Antibody-APC (4F225) 可用于 FCM。

Anti-ESAM Antibody-APC (4F225)

Anti-ESAM Antibody-APC (4F225)

Rating icon 还可以
Anti-ESAM Antibody-APC (4F225)
产品编号 TMAY-00424A 别名 endothelial cell adhesion molecule

Anti-ESAM Antibody-APC (4F225) 是一种 APC-conjugated Rabbit 抗体,靶向 ESAM。Anti-ESAM Antibody-APC (4F225) 可用于 FCM。

规格价格库存数量
25 T
¥ 1,080
5日内发货
100 T
¥ 2,195
5日内发货
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TargetMol 的所有产品仅用作科学研究或药证申报,不能被用于人体,我们不向个人提供产品和服务。请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
化合物带有盐酸盐离子、硫酸盐离子等是否和其本身有什么区别?盐形式和游离态有什么区别?
盐和非盐形式化合物的活性分子是一样的,在生物实验中起到的效果也一致,活性和使用方法都是一样的。只是由于呈盐不同,物理性质比如溶解度会有差异。建议您根据溶解、实验需求进行选择。
如何选择某个靶点的特异性或总的抑制剂?特异性和非特异性的区别是什么?
抑制剂按照特异性分为广谱 pan 和特异性 selective 两种。Pan 为某个靶点总的抑制剂,对所有亚型或整个家族的成员都有抑制作用。Selective 抑制剂针对某个蛋白激酶的某个亚型或家族中某个成员抑制率特别高或有特异性抑制作用。 一般评价一个抑制剂的抑制效率主要看 IC50 值,IC50 值越低,说明抑制剂效率越高。建议您根据以上几个特征进行综合选择,也可联系技术帮您推荐相关抑制剂。
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产品介绍

生物活性
产品描述
Anti-ESAM Antibody-APC (4F225) is a APC-conjugated Rabbit antibody targeting ESAM. Anti-ESAM Antibody-APC (4F225) can be used in FCM.
别名endothelial cell adhesion molecule
Ig Type
Rabbit IgG
克隆号
4F225
交叉反应
Human
验证活性
Profile of anti-ESAM reactivity on HUVEC cells analyzed by flow cytometry.
应用
推荐剂量
5 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human ESAM (rh ESAM; TMPY-01312; NP_620411.2; Met 1-Ala 248) and conjugated with APC under optimum conditions, the unreacted APC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.09% sodium azide
研究背景Endothelial cell-selective adhesion molecule (ESAM) is a member of JAM family of immunoglobulin superfamily and consists of one V-type and one C2-type immunoglobulin domain, as well as a hydrophobic signal sequence, a single transmembrane region, and a cytoplasmic domain. It is specifically expressed at endothelial tight junctions and on activated platelets. ESAM at endothelial tight junctions participates in the migration of neutrophils through the vessel wall, possibly by influencing endothelial cell contacts. The adaptor protein membrane-associated guanylate kinase MAGI-1 has been identified as an intracellular binding partner of ESAM. Previous studies have indicated that ESAM regulates angiogenesis in the primary tumor growth and endothelial permeability. It suggest that ESAM has a redundant functional role in physiological angiogenesis but serves a unique and essential role in pathological angiogenic processes such as tumor growth.
偶联与修饰
偶联
APC
其他可选修饰符
Unconjugated/FITC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Protein: Human ESAM protein (TMPY-01312)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
运输方式Shipping with blue ice.

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