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Clusterin Protein, Human, Recombinant (CLU34, His)

Clusterin Protein, Human, Recombinant (CLU34, His)

产品编号 TMPY-01691
别名: SGP-2, AAG4, KUB1, CLI, CLU2, TRPM2, APO-J, SP-40, CLU1, clusterin, APOJ, TRPM-2, NA1/NA2, SGP2

Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2.

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Clusterin Protein, Human, Recombinant (CLU34, His)
规格 价格/CNY 货期 数量
50 μg ¥ 2,260 现货
100 μg ¥ 3,970 5日内发货
200 μg ¥ 6,930 5日内发货
500 μg ¥ 14,440 5日内发货
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产品目录号及名称: Clusterin Protein, Human, Recombinant (CLU34, His) (TMPY-01691)
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生物活性 Testing in progress
产品描述 Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2.
种属 Human
表达系统 HEK293 Cells
标签 C-His
蛋白编号 P10909-2
别名 SGP-2, AAG4, KUB1, CLI, CLU2, TRPM2, APO-J, SP-40, CLU1, clusterin, APOJ, TRPM-2, NA1/NA2, SGP2
蛋白构建 The Human CLU isoform long (NP_001822.2) (Met 1-Glu 501) was expressed, with a C-terminal polyhistidine tag.
蛋白纯度 > 92 % as determined by SDS-PAGE

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分子量 51.5 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. Clusterin/Apolipoprotein J/Apo-J is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others.

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Keywords

Clusterin Protein, Human, Recombinant (CLU34, His) TRPM 2 CLU 2 SGP-2 SGP 2 AAG-4 AAG4 KUB-1 KUB1 CLI CLU2 CLU-2 SP 40 KUB 1 TRPM2 APO-J AAG 4 SP-40 CLU1 SP40 CLU-1 clusterin CLU 1 APOJ TRPM-2 NA1/NA2 SGP2 recombinant recombinant-proteins proteins protein

 

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