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Anti-Acetyl-Histone H4 (Lys5/8/12/16) Antibody (5M744)

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产品编号 TMAB-02226

种类:Recombinant Mouse Monoclonal
应用:WB,IHC-P,IHC-Fr,ICC/IF,IF
交叉反应:Human (predicted:Mouse,Rat)

Anti-Acetyl-Histone H4 (Lys5/8/12/16) Antibody (5M744)

Anti-Acetyl-Histone H4 (Lys5/8/12/16) Antibody (5M744)

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-02226

种类:Recombinant Mouse Monoclonal
应用:WB,IHC-P,IHC-Fr,ICC/IF,IF
交叉反应:Human (predicted:Mouse,Rat)

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产品介绍

生物活性
产品描述
Anti-Acetyl-Histone H4 (Lys5/8/12/16) Antibody (5M744) is a Mouse antibody targeting Acetyl-Histone H4 (Lys5/8/12/16). Anti-Acetyl-Histone H4 (Lys5/8/12/16) Antibody (5M744) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
克隆号
5M744
交叉反应
Human (predicted:Mouse,Rat)
应用WBIHC-PIHC-FrICC/IFIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-100; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Nucleus. Chromosome.
构建方式Recombinant Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq, Jul 2008]
抗原信息
基因名称
H4C1
基因ID
蛋白名称
Histone H4
功能
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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