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Anti-Phospho-CK18 (Ser60) Polyclonal Antibody

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货号 TMAB-10514

Anti-Phospho-CK18 (Ser60) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-CK18 (Ser60)。Anti-Phospho-CK18 (Ser60) Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

Anti-Phospho-CK18 (Ser60) Polyclonal Antibody

Anti-Phospho-CK18 (Ser60) Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-10514

Anti-Phospho-CK18 (Ser60) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-CK18 (Ser60)。Anti-Phospho-CK18 (Ser60) Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
50 μL
¥ 1,170
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100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-CK18 (Ser60) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CK18 (Ser60). Anti-Phospho-CK18 (Ser60) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrICC/IFIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, perinuclear region. Nucleus, nucleolus.
组织特异性Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human CK18 around the phosphorylation site of Ser60
抗原种属
Human
基因名称
KRT18
基因ID
3875
蛋白名称
Keratin, type I cytoskeletal 18
Uniprot ID
P05783
功能
When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
化学信息
分子量Theoretical: 48 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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