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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-EIF4G1 (Ser1238) Polyclonal Antibody

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货号 TMAB-10642

Anti-Phospho-EIF4G1 (Ser1238) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-EIF4G1 (Ser1238)。Anti-Phospho-EIF4G1 (Ser1238) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Phospho-EIF4G1 (Ser1238) Polyclonal Antibody

Anti-Phospho-EIF4G1 (Ser1238) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10642

Anti-Phospho-EIF4G1 (Ser1238) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-EIF4G1 (Ser1238)。Anti-Phospho-EIF4G1 (Ser1238) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-EIF4G1 (Ser1238) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EIF4G1 (Ser1238). Anti-Phospho-EIF4G1 (Ser1238) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq]. eIF4G1 (eukaryotic translation Initiation Factor 4 Gamma 1) is a component of the protein complex eIF-4 which is involved in the recognition of the mRNA cap ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of mRNA to the ribosome. eIF4G plays a critical role in protein expression and is at the center of a complex regulatory network. Together with the cap-binding protein eIF4E, it recruits the small ribosomal subunit to the 5'-end of mRNA and promotes the assembly of a functional translation initiation complex which scans along the mRNA to the translation start codon. Human eIF4G contains three consecutive HEAT domains, as well as long unstructured regions involved in multiple protein-protein interactions. The interactions of eIF4G1 with other factors are largely unknown.
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human EIF4G1 around the phosphorylation site of Ser1238
抗原种属
Human
基因名称
EIF4G1
基因ID
1981
蛋白名称
Eukaryotic translation initiation factor 4 gamma 1
Uniprot ID
Q04637
功能
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.
化学信息
分子量Theoretical: 175 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
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