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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NCOA3 Polyclonal Antibody

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货号 TMAB-09284

Anti-NCOA3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NCOA3。Anti-NCOA3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-NCOA3 Polyclonal Antibody

Anti-NCOA3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09284

Anti-NCOA3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NCOA3。Anti-NCOA3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-NCOA3 Polyclonal Antibody is a Rabbit antibody targeting NCOA3. Anti-NCOA3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrICC/IFIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; FCM: 2μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Mainly cytoplasmic and weakly nuclear. Upon TNF activation and subsequent phosphorylation, it translocates from the cytoplasm to the nucleus.
组织特异性Widely expressed. High expression in heart, skeletal muscle, pancreas and placenta. Low expression in brain, and very low in lung, liver and kidney.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq, Mar 2010].
抗原信息
免疫原
KLH conjugated synthetic peptide: human ATR/ACTR
抗原种属
Human
基因名称
NCOA3
基因ID
8202
蛋白名称
Nuclear receptor coactivator 3
Uniprot ID
Q9Y6Q9
功能
Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit. Interacts with PSMB9.
化学信息
分子量Theoretical: 309 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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