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Anti-MFN1 Antibody (2T242)

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Anti-MFN1 Antibody (2T242)
产品编号 TMAC-02590
别名 Transmembrane GTPase MFN1, Mitofusin-1, MFN 1, Fzo homolog

Anti-MFN1 Antibody (2T242) 是一种 Rabbit 抗体,靶向 MFN1。Anti-MFN1 Antibody (2T242) 可用于 WB,IP,FCM。

Anti-MFN1 Antibody (2T242)

Anti-MFN1 Antibody (2T242)

Rating icon 还可以
Anti-MFN1 Antibody (2T242)
产品编号 TMAC-02590 别名 Transmembrane GTPase MFN1, Mitofusin-1, MFN 1, Fzo homolog

Anti-MFN1 Antibody (2T242) 是一种 Rabbit 抗体,靶向 MFN1。Anti-MFN1 Antibody (2T242) 可用于 WB,IP,FCM。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-MFN1 Antibody (2T242) is a Rabbit antibody targeting MFN1. Anti-MFN1 Antibody (2T242) can be used in WB,IP,FCM.
别名Transmembrane GTPase MFN1, Mitofusin-1, MFN 1, Fzo homolog
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of Mitofusin 1 on K562 cells lysates using anti-Mitofusin 1 antibody at 1/1,000 dilution.
2. Flow cytometric analysis of 293 cells with Mitofusin 1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
推荐剂量
WB: 1:1000-2000; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Mitofusin 1 (Mfn1) and mitofusin 2 (Mfn2) are homologs for the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins and are mediators of mitochondrial fusion. A GTPase domain is required for Mfn protein function but the molecular mechanisms of the GTPase-dependent reaction as well as the functional division of the two Mfn proteins are unknown. They are essential for embryonic development and may play a role in the pathobiology of obesity. Although the Mfn1 and Mfn2 genes are broadly expressed, they show different levels of expression in different tissues. Two Mfn1 transcripts are elevated in heart, while Mfn2 mRNA is abundantly expressed in heart and muscle tissue but present only at low levels in many other tissues. Mfn1 localizes to mitochondria and participates in at least two different high molecular weight protein complexes in a GTP-dependent manner. Purified recombinant Mfn1 exhibited approximately eightfold higher GTPase activity than Mfn2.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 84 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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