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Anti-MRP2 Antibody (3L876)

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Anti-MRP2 Antibody (3L876)
产品编号 TMAC-02648
别名 multidrug resistance-associated protein2, Multidrug resistance associated protein 2, MRP2, MRP 2, KIAA1010, DJS, cMRP, CMOAT1, CMOAT, Canalicular multispecific organic anion transporter 1, Canalicular multidrug resistance protein, ATP-binding cassette sub-family C member 2, ATP binding cassette subfamily C member 2, ATP binding cassette sub family C(CFTR/MRP) member 2, ABCC2, ABC30

Anti-MRP2 Antibody (3L876) 是一种 Rabbit 抗体,靶向 MRP2。Anti-MRP2 Antibody (3L876) 可用于 WB,ICC,IHC,FCM。

Anti-MRP2 Antibody (3L876)

Anti-MRP2 Antibody (3L876)

Rating icon 还可以
Anti-MRP2 Antibody (3L876)
产品编号 TMAC-02648 别名 multidrug resistance-associated protein2, Multidrug resistance associated protein 2, MRP2, MRP 2, KIAA1010, DJS, cMRP, CMOAT1, CMOAT, Canalicular multispecific organic anion transporter 1, Canalicular multidrug resistance protein, ATP-binding cassette sub-family C member 2, ATP binding cassette subfamily C member 2, ATP binding cassette sub family C(CFTR/MRP) member 2, ABCC2, ABC30

Anti-MRP2 Antibody (3L876) 是一种 Rabbit 抗体,靶向 MRP2。Anti-MRP2 Antibody (3L876) 可用于 WB,ICC,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-MRP2 Antibody (3L876) is a Rabbit antibody targeting MRP2. Anti-MRP2 Antibody (3L876) can be used in WB,ICC,IHC,FCM.
别名multidrug resistance-associated protein2, Multidrug resistance associated protein 2, MRP2, MRP 2, KIAA1010, DJS, cMRP, CMOAT1, CMOAT, Canalicular multispecific organic anion transporter 1, Canalicular multidrug resistance protein, ATP-binding cassette sub-family C member 2, ATP binding cassette subfamily C member 2, ATP binding cassette sub family C(CFTR/MRP) member 2, ABCC2, ABC30
Ig Type
IgG
交叉反应
Human
验证活性
1. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-MRP2 antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-MRP2 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-MRP2 antibody. Counter stained with hematoxylin.
4. ICC staining MRP2 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining MRP2 in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. Flow cytometric analysis of A549 cells with MRP2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
7. Western blot analysis of MRP2 on different lysates with MRP2 at 1/2,000 dilution. Lane 1: HepG2 cell lysate, Lane 2: A549 cell lysate, Lane 3: HeLa cell lysate (negative) Lysates/proteins at 15 ug/Lane. Predicted band size: 174 kDa, Observed band size: 300 kDa, Exposure time: 5 minutes; 4-20% SDS-PAGE gel.
应用
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Multi-drug resistance protein 2 (MRP2), also known as ABCC2, is an ATP binding cassette (ABC) transporter responsible for biliary excretion of xenobiotics, endobiotics, and their metabolites. Deficiency in ABCC2 results in the clinical disorder Dubin-Johnson syndrome. MRP2 is found to be expressed in a variety of human cancers, and is associated with resistance of tumor cells to various anticancer drugs including cisplatin. The predicted molecular weight of MRP2 is 174 kDa, while mature MRP2 usually has a slower migration around 190-250 kDa due to the glycosylation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 174 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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