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BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc)

产品编号 TMPY-00680

别名: bone morphogenetic protein 2

BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.5 kDa and the accession number is C8C060.

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BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc)

规格	价格/CNY		货期	数量
20 μg	￥ 1,350		现货
100 μg	￥ 3,430		现货

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生物活性	Testing in progress
产品描述	BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.5 kDa and the accession number is C8C060.

种属	Human,Mouse,Rat,Rhesus,Canine
表达系统	HEK293 Cells
标签	N-hFc
蛋白编号	C8C060
别名	bone morphogenetic protein 2
蛋白构建	The mature form of Human / Mouse / Rat / rhesus / canine BMP2 (NP_001191.1) (Gln 283-Arg 396) was fused with the Fc region of Human IgG1 at the N-terminus. The mature form sequences of Human, Mouse, Rat, rhesus and canine BMP2 are identical.
蛋白纯度	> 95 % as determined by SDS-PAGE.
分子量	39.5 kDa (predicted)

内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.

参考文献

1. Jiao X, et al. (2007) Heparan sulfate proteoglycans (HSPGs) modulate BMP-2 osteogenic bioactivity in C2C12 cells. J Biol Chem. 282(2):1080-6. 2. Michon F, et al. (2008) BMP-2 and BMP-7 play antagonistic roles in feather induction. Development 135 (16):2797-805.

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Keywords

BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc) bone morphogenetic protein 2 recombinant recombinant-proteins proteins protein

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