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Anti-MBP Antibody (3G275)

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货号 TMAB-08649

Anti-MBP Antibody (3G275) 是一种 Mouse 抗体,靶向 MBP。Anti-MBP Antibody (3G275) 可用于 IHC-P,IHC-Fr,IF,WB。

Anti-MBP Antibody (3G275)

Anti-MBP Antibody (3G275)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08649

Anti-MBP Antibody (3G275) 是一种 Mouse 抗体,靶向 MBP。Anti-MBP Antibody (3G275) 可用于 IHC-P,IHC-Fr,IF,WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-MBP Antibody (3G275) is a Mouse antibody targeting MBP. Anti-MBP Antibody (3G275) can be used in IHC-P,IHC-Fr,IF,WB.
Ig Type
IgG1, k
克隆号
3G275
反应种属
Human,Mouse,Rat
应用IHC-PIHC-FrIFWB
推荐剂量
IHC-P: 1:200-1000; IHC-Fr: 1:200-1000; IF: 1:200-1000; WB: 1:1000-2000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Myelin membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic side of myelin.
组织特异性MBP isoforms are found in both the central and the peripheral nervous system, whereas Golli-MBP isoforms are expressed in fetal thymus, spleen and spinal cord, as well as in cell lines derived from the immune system.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Oligodendrocyte Marker The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.
抗原信息
免疫原
KLH conjugated synthetic peptide: human MBP
抗原种属
Human
基因名称
MBP
基因ID
蛋白名称
Myelin basic protein
Uniprot ID
功能
The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
化学信息
分子量Theoretical: 33 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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