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Anti-p67phox Antibody (9W409) 是一种 Rabbit 抗体,靶向 p67phox。Anti-p67phox Antibody (9W409) 可用于 WB,IHC,IP。
Anti-p67phox Antibody (9W409) 是一种 Rabbit 抗体,靶向 p67phox。Anti-p67phox Antibody (9W409) 可用于 WB,IHC,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,480 | 5日内发货 |
产品描述 | Anti-p67phox Antibody (9W409) is a Rabbit antibody targeting p67phox. Anti-p67phox Antibody (9W409) can be used in WB,IHC,IP. |
别名 | P67-PHOX, P67PHOX, NOXA2, neutrophil cytosolic factor 2, NCF-2 |
Ig Type | IgG |
克隆号 | 9W409 |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of NOXA2 on rat spleen tissue lysate using anti-NOXA2 antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded rat spleen tissue using anti-NOXA2 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-NOXA2 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using anti-NOXA2 antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:500; IHC: 1:50-200; IP: 1:10-50 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | The heredity disease chronic granulomatous disease (CGF) has been linked to mutations in p47phox and p67phox. The cytosolic proteins p47phox and p67phox, also designated neutrophil cytosol factor 1(NCF1) and NCF2, respectively, are required for activation of the superoxide-producing NADPH oxidase in neutrophils and other phagocytic cells. During activation of the NADPH oxidase, p47phox and p67phox migrate to the plasma membrane where they associate with cytochrome b558 and the small G protein Rac to form the functional enzyme complex. Both p47phox and p67phox contain two Src homology 3 (SH3) domains. The C-terminal SH3 domain of p67phox has been shown to interact with the proline rich domain of p47phox, suggesting that p47phox may faciliate the transport of p67phox to the membrane. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein: Human NOXA2 aa 150-300 |
抗原种属 | human |
Uniprot ID |
分子量 | Theoretical: 60/47 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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