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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NALP2 Polyclonal Antibody

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货号 TMAB-09214

Anti-NALP2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NALP2。Anti-NALP2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-NALP2 Polyclonal Antibody

Anti-NALP2 Polyclonal Antibody

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货号 TMAB-09214

Anti-NALP2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NALP2。Anti-NALP2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-NALP2 Polyclonal Antibody is a Rabbit antibody targeting NALP2. Anti-NALP2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Horse,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Expressed at high levels in lung, placenta and thymus and at lower levels in ovary, intestine and brain.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human NACHT, LRR and PYD domains-containing protein 2
抗原种属
Human
基因名称
NLRP2
基因ID
55655
蛋白名称
NACHT, LRR and PYD domains-containing protein 2
Uniprot ID
Q9NX02
功能
Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
化学信息
分子量Theoretical: 117 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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