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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PDE4D Polyclonal Antibody

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货号 TMAB-10112

Anti-PDE4D Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PDE4D。Anti-PDE4D Polyclonal Antibody 可用于 WB,FCM。

Anti-PDE4D Polyclonal Antibody

Anti-PDE4D Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-10112

Anti-PDE4D Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PDE4D。Anti-PDE4D Polyclonal Antibody 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-PDE4D Polyclonal Antibody is a Rabbit antibody targeting PDE4D. Anti-PDE4D Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Pig,Cow,Horse,Rabbit)
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Membrane. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, centrosome. Note=Found in the soluble fraction, associated with membranes, and associated with the cytoskeleton and the centrosome.
组织特异性Widespread; most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Cyclic AMP-dependent phosphodiesterase type D (PDE4D) family is comprise of 5 variants (PDE4D1, D2, D3, D4 and D5). One or more PDE4D subtype variants are ubiquitously present in all mammalian cells. In CNS all five PDE4D subtype variants are expressed in varying ratios and their activity is regulated in tandem with GPCRs stimulation. Peripheral tissues also exhibit differential expression of PDE4D variants. PDE4D1/D2 mRNA levels rise in response to an increase in cAMP. Short term regulation of PDE4D variants involved PKA, MAP kinases and Erk2 phosphorylation that results in rapid change in their enzymatic activities. Other regulatory mechanism involved protein protein interactions with cytoskeletal scaffolding proteins.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PDE4D
抗原种属
Human
基因名称
PDE4D
基因ID
5144
蛋白名称
cAMP-specific 3', 5'-cyclic phosphodiesterase 4D
Uniprot ID
Q08499
功能
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
化学信息
分子量Theoretical: 90 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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