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Anti-JAML Antibody-HRP (9E630)

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产品编号 TMAY-00299H
别名 Gm638, Crea7, AMICA, adhesion molecule, interacts with CXADR antigen 1

Anti-JAML Antibody-HRP (9E630) 是一种 HRP-conjugated Mouse 抗体,靶向 JAML。Anti-JAML Antibody-HRP (9E630) 可用于 ELISA。

Anti-JAML Antibody-HRP (9E630)

Anti-JAML Antibody-HRP (9E630)

Rating icon 还可以
产品编号 TMAY-00299H 别名 Gm638, Crea7, AMICA, adhesion molecule, interacts with CXADR antigen 1

Anti-JAML Antibody-HRP (9E630) 是一种 HRP-conjugated Mouse 抗体,靶向 JAML。Anti-JAML Antibody-HRP (9E630) 可用于 ELISA。

规格价格库存数量
100 μg
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-JAML Antibody-HRP (9E630) is a HRP-conjugated Mouse antibody targeting JAML. Anti-JAML Antibody-HRP (9E630) can be used in ELISA.
别名Gm638, Crea7, AMICA, adhesion molecule, interacts with CXADR antigen 1
Ig Type
Monoclonal Mouse IgG1
克隆号
9E630
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 0.1-1 μg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human JAML / AMICA1 (rh JAML / AMICA1; TMPY-01164; NP_001091996.1; Met1-Leu275). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Junctional adhesion molecules (JAMs) are endothelial and epithelial adhesion molecules involved in the recruitment of circulating leukocytes to inflammatory sites. JAML (Junctional adhesion molecule-like), also known as AMICA1 (Adhesion molecule interacting with CXADR antigen 1), a protein related to the JAM family, is restricted to leukocytes and promotes their adhesion to endothelial cells. It contains 2 extracellular immunoglobulin-like domains, a transmembrane segment, and a cytoplasmic tail involved in activation signaling. Monocytic JAML/AMICA1 plays a critical role in regulating monocyte transendothelial migration (TEM) probably via binding to the endothelial coxsackie and adenovirus receptor (CAR) and other tight junction-associated adhesive molecules. The Expression of JAML/AMICA1 is restricted to the hematopoietic tissues with the exception of liver. JAML may function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, JAML/AMICA1 also enhances myeloid leukemia cell adhesion to endothelial cells.
偶联与修饰
偶联
HRP
其他可选修饰符
Unconjugated
可提供抗体种类
2
抗原信息
免疫原
Recombinant Human JAML / AMICA1 Protein (TMPY-01164)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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